Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]

quorum-sensing sigma-54 dependent transcriptional regulator LuxO


LOCUS       WP_005298395             479 aa            linear   BCT 31-JUL-2023
            [Photobacterium damselae].
ACCESSION   WP_005298395
VERSION     WP_005298395.1
KEYWORDS    RefSeq.
SOURCE      Photobacterium damselae
  ORGANISM  Photobacterium damselae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Vibrionales; Vibrionaceae; Photobacterium.
REFERENCE   1  (residues 1 to 479)
  AUTHORS   Raychaudhuri,S., Jain,V. and Dongre,M.
  TITLE     Identification of a constitutively active variant of LuxO that
            affects production of HA/protease and biofilm development in a
            non-O1, non-O139 Vibrio cholerae O110
  JOURNAL   Gene 369, 126-133 (2006)
   PUBMED   16376028
REFERENCE   2  (residues 1 to 479)
  AUTHORS   Lilley,B.N. and Bassler,B.L.
  TITLE     Regulation of quorum sensing in Vibrio harveyi by LuxO and sigma-54
  JOURNAL   Mol Microbiol 36 (4), 940-954 (2000)
   PUBMED   10844680
REFERENCE   3  (residues 1 to 479)
  AUTHORS   Freeman,J.A. and Bassler,B.L.
  TITLE     A genetic analysis of the function of LuxO, a two-component
            response regulator involved in quorum sensing in Vibrio harveyi
  JOURNAL   Mol Microbiol 31 (2), 665-677 (1999)
   PUBMED   10027982
REFERENCE   4  (residues 1 to 479)
  AUTHORS   Klose,K.E., Novik,V. and Mekalanos,J.J.
  TITLE     Identification of multiple sigma54-dependent transcriptional
            activators in Vibrio cholerae
  JOURNAL   J Bacteriol 180 (19), 5256-5259 (1998)
   PUBMED   9748465
REFERENCE   5  (residues 1 to 479)
  AUTHORS   Bassler,B.L., Wright,M. and Silverman,M.R.
  TITLE     Sequence and function of LuxO, a negative regulator of luminescence
            in Vibrio harveyi
  JOURNAL   Mol Microbiol 12 (3), 403-412 (1994)
   PUBMED   8065259
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF041946.1
            Evidence Source    :: NCBIFAM
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..479
                     /organism="Photobacterium damselae"
                     /db_xref="taxon:38293"
     gene            1..479
                     /gene="luxO"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
     Protein         1..479
                     /product="quorum-sensing sigma-54 dependent
                     transcriptional regulator LuxO"
                     /GO_function="GO:0043565 - sequence-specific DNA binding
                     [Evidence IEA]"
                     /GO_process="GO:0000160 - phosphorelay signal transduction
                     system [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /calculated_mol_wt=52655
     Region          6..473
                     /region_name="AtoC"
                     /note="DNA-binding transcriptional response regulator,
                     NtrC family, contains REC, AAA-type ATPase, and a Fis-type
                     DNA-binding domains [Signal transduction mechanisms];
                     COG2204"
                     /db_xref="CDD:441806"
ORIGIN      
        1 mesksrqkqv lmvedtasva alyksylnpl glnvnivgtg kealsfihdi vpdlilldlr
       61 lpdmtgievl aavrelhpdl avvimtahgs idvaveamrh gaqdflikpc eadrlritvn
      121 nvlkqehksn aepkskqsga qyqgfignsl amqavyrvie saasskatvf itgesgtgke
      181 vcaeaihaas prhdkpfval ncaaipkeli eselfghvkg aftgasserq gaveladngt
      241 lfldelcemd ldlqskllrf iqsgtyqkvg ssktntvdvr fvcatnrnpw vevqegrfre
      301 dlyyrlhvip inlpplrerg sdvieiahal lgmtsveegk dftrfapdvv eyfqkynwpg
      361 nirelqnvir nivvlhsgev vttemlpppl nqdiganiad tvhsvsnhsl eqntysladr
      421 snesvhnnki eplwivekra iqkaidacdg nipraaglle vspstiyrkl qawqdaask