tRNA dihydrouridine synthase DusB [Shigella flexneri].

LOCUS       WP_005115913             280 aa            linear   BCT 01-JUL-2024
ACCESSION   WP_005115913
VERSION     WP_005115913.1
KEYWORDS    RefSeq.
SOURCE      Shigella flexneri
  ORGANISM  Shigella flexneri
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Shigella.
REFERENCE   1  (residues 1 to 280)
  AUTHORS   Morett,E. and Bork,P.
  TITLE     Evolution of new protein function: recombinational enhancer Fis
            originated by horizontal gene transfer from the transcriptional
            regulator NtrC
  JOURNAL   FEBS Lett 433 (1-2), 108-112 (1998)
   PUBMED   9738943
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00737.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..280
                     /organism="Shigella flexneri"
                     /db_xref="taxon:623"
     gene            1..280
                     /gene="dusB"
     Protein         1..280
                     /product="tRNA dihydrouridine synthase DusB"
                     /EC_number="1.3.1.-"
                     /GO_function="GO:0017150 - tRNA dihydrouridine synthase
                     activity [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /GO_process="GO:0008033 - tRNA processing [Evidence IEA]"
                     /calculated_mol_wt=31077
     Region          1..280
                     /region_name="TIM-like beta/alpha barrel domains"
                     /note="A large family of domains similar to triose
                     phosphate isomerase (TIM) which, in general, share an
                     eight beta/alpha closed barrel structure; cl21457"
                     /db_xref="CDD:473867"
     Site            order(29,59..60,98,100,127..128,130..131,160..161,184)
                     /site_type="active"
                     /db_xref="CDD:239200"
     Site            order(59,100,128,130)
                     /site_type="active"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:239200"
     Site            order(60,98,127,131,160..161)
                     /site_type="other"
                     /note="substrate binding site [chemical binding]"
                     /db_xref="CDD:239200"
ORIGIN      
        1 mssnpqvwes dksrlrmvhi depgirtvqi agsapkemad aarinvesga qiidinmgcp
       61 akkvnrklag sallqypdvv ksiltevvna vdvpvtlkir tgwapehrnc eeiaqlaedc
      121 giqaltihgr traclfngea eydsiravkq kvsipviang ditdplkara vldytgadal
      181 migraaqgrp wifreiqhyl dtgellpplp laevkrllca hvrelhdfyg pakgyriark
      241 hvswylqeha pndqfrrtfn aiedaseqle aleayfenfa