type I pantothenate kinase [Shigella flexneri].

LOCUS       WP_005100331             308 aa            linear   BCT 29-APR-2021
ACCESSION   WP_005100331
VERSION     WP_005100331.1
KEYWORDS    RefSeq.
SOURCE      Shigella flexneri
  ORGANISM  Shigella flexneri
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Shigella.
REFERENCE   1  (residues 1 to 308)
  AUTHORS   Song,W.J. and Jackowski,S.
  TITLE     Kinetics and regulation of pantothenate kinase from Escherichia
            coli
  JOURNAL   J Biol Chem 269 (43), 27051-27058 (1994)
   PUBMED   7929447
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00554.2
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..308
                     /organism="Shigella flexneri"
                     /db_xref="taxon:623"
     gene            1..308
                     /gene="coaA"
     Protein         1..308
                     /product="type I pantothenate kinase"
                     /EC_number="2.7.1.33"
                     /GO_function="GO:0004594 - pantothenate kinase activity
                     [Evidence IEA]"
                     /GO_process="GO:0015937 - coenzyme A biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=35326
     Region          19..308
                     /region_name="panK_bact"
                     /note="pantothenate kinase, bacterial type; TIGR00554"
                     /db_xref="CDD:273134"
     Site            order(90,93..96,231,235,295,299)
                     /site_type="other"
                     /note="ATP-binding site [chemical binding]"
                     /db_xref="CDD:238983"
     Site            order(93..94,98,169,235,239,299)
                     /site_type="other"
                     /note="CoA-binding site [chemical binding]"
                     /db_xref="CDD:238983"
     Site            order(94,191)
                     /site_type="other"
                     /note="Mg2+-binding site [ion binding]"
                     /db_xref="CDD:238983"
ORIGIN      
        1 mtpylqfdrn qwaalrdsvp mtlsedeiar lkginedlsl eevaeiylpl srllnfyiss
       61 nlrrqavleq flgtngqrip yiisiagsva vgksttarvl qallsrwpeh rrvelittdg
      121 flhpnqvlke rglmkkkgfp esydmhrlvk fvsdlksgvp nvtapvyshl iydvipdgdk
      181 tvvqpdilil eglnvlqsgm dyphdphhvf vsdfvdfsiy vdapedllqt wyinrflkfr
      241 egaftdpdsy fhnyakltke eaiktamtlw keinwlnlkq nilptreras liltksanhv
      301 veevrlrk