terminase large subunit [Shigella flexneri].

LOCUS       WP_005047991             492 aa            linear   BCT 31-DEC-2024
ACCESSION   WP_005047991
VERSION     WP_005047991.1
KEYWORDS    RefSeq.
SOURCE      Shigella flexneri
  ORGANISM  Shigella flexneri
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Shigella.
REFERENCE   1  (residues 1 to 492)
  AUTHORS   Fung,H.K.H., Grimes,S., Huet,A., Duda,R.L., Chechik,M., Gault,J.,
            Robinson,C.V., Hendrix,R.W., Jardine,P.J., Conway,J.F.,
            Baumann,C.G. and Antson,A.A.
  TITLE     Structural basis of DNA packaging by a ring-type ATPase from an
            archetypal viral system
  JOURNAL   Nucleic Acids Res 50 (15), 8719-8732 (2022)
   PUBMED   35947691
REFERENCE   2  (residues 1 to 492)
  AUTHORS   Xu,R.G., Jenkins,H.T., Chechik,M., Blagova,E.V., Lopatina,A.,
            Klimuk,E., Minakhin,L., Severinov,K., Greive,S.J. and Antson,A.A.
  TITLE     Viral genome packaging terminase cleaves DNA using the canonical
            RuvC-like two-metal catalysis mechanism
  JOURNAL   Nucleic Acids Res 45 (6), 3580-3590 (2017)
   PUBMED   28100693
REFERENCE   3  (residues 1 to 492)
  AUTHORS   Black,L.W.
  TITLE     DNA packaging in dsDNA bacteriophages
  JOURNAL   Annu Rev Microbiol 43, 267-292 (1989)
   PUBMED   2679356
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11468530
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..492
                     /organism="Shigella flexneri"
                     /db_xref="taxon:623"
     Protein         1..492
                     /product="terminase large subunit"
                     /EC_number="3.6.4.-"
                     /GO_function="GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0140657 - ATP-dependent activity
                     [Evidence IEA]"
                     /calculated_mol_wt=55320
     Region          1..474
                     /region_name="YmfN"
                     /note="Phage terminase-like protein, large subunit,
                     contains N-terminal HTH domain [Mobilome: prophages,
                     transposons]; COG4626"
                     /db_xref="CDD:443665"
ORIGIN      
        1 mrgrpielep wqqfafacil gfkvkatgrr kytsafievp rknaksttaa ilanwflime
       61 ngqqdiytaa vsrdqarivf dnarqmclls rplrrrvniq ahkvihpksn sllkplaaka
      121 atiegtnpsl sivdeyhlhp dngvysalel gmgarpegll faittsgsnv vsackqhydy
      181 ccqildgeev ndsifvliye lddenevddp amwikanpni dvsvdrekla stiqkargip
      241 sqwvemmtkr fniwcqgttp wmgngawaec agtfteedlh gqecyagldl sstsdissvc
      301 yafpvgktim lisrhylpef qlqnpanknr avyrqwakag wirttpgdci dydrirddim
      361 qdaekfnirl vgfdtwnath lrtqlqgagf evepfpqtyl rfspaaksfe vfvnrrvivh
      421 rgdpvlswsm snvvmqsdan anikpnkkks pnkidpsvaa lmafgtfqae hedfafdisd
      481 shrqkleefs gv