MULTISPECIES: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase

LOCUS       WP_004735397             159 aa            linear   BCT 29-APR-2021
            [Vibrio].
ACCESSION   WP_004735397
VERSION     WP_004735397.1
KEYWORDS    RefSeq.
SOURCE      Vibrio
  ORGANISM  Vibrio
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Vibrionales; Vibrionaceae.
REFERENCE   1  (residues 1 to 159)
  AUTHORS   Narayanasamy,P., Eoh,H., Brennan,P.J. and Crick,D.C.
  TITLE     Synthesis of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate
            and kinetic studies of Mycobacterium tuberculosis IspF
  JOURNAL   Chem Biol 17 (2), 117-122 (2010)
   PUBMED   20189102
REFERENCE   2  (residues 1 to 159)
  AUTHORS   Herz,S., Wungsintaweekul,J., Schuhr,C.A., Hecht,S., Luttgen,H.,
            Sagner,S., Fellermeier,M., Eisenreich,W., Zenk,M.H., Bacher,A. and
            Rohdich,F.
  TITLE     Biosynthesis of terpenoids: YgbB protein converts
            4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate to
            2C-methyl-D-erythritol 2,4-cyclodiphosphate
  JOURNAL   Proc Natl Acad Sci U S A 97 (6), 2486-2490 (2000)
   PUBMED   10694574
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00151.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..159
                     /organism="Vibrio"
                     /db_xref="taxon:662"
     gene            1..159
                     /gene="ispF"
     Protein         1..159
                     /product="2-C-methyl-D-erythritol 2,4-cyclodiphosphate
                     synthase"
                     /EC_number="4.6.1.12"
                     /GO_function="GO:0008685 - 2-C-methyl-D-erythritol
                     2,4-cyclodiphosphate synthase activity [Evidence IEA]"
                     /GO_process="GO:0019288 - isopentenyl diphosphate
                     biosynthetic process, methylerythritol 4-phosphate pathway
                     [Evidence IEA]"
                     /calculated_mol_wt=16813
     Region          1..157
                     /region_name="IspF"
                     /note="2C-methyl-D-erythritol 2,4-cyclodiphosphate
                     synthase [Lipid transport and metabolism]; COG0245"
                     /db_xref="CDD:440015"
ORIGIN      
        1 mirighgfdv hkfggegpvi iggvsvpyeq gliahsdgdv alhalcdall gsiaagdigr
       61 hfpdtddewk gadsrellkd vyrrvkeqgy vignaditim aqapkmaphi dsmcqaiaqd
      121 letsisnvnv kattterlgf tgrkegiace avvlitksa