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LOCUS WP_004727256 324 aa linear BCT 23-DEC-2024 ACCESSION WP_004727256 VERSION WP_004727256.1 KEYWORDS RefSeq. SOURCE Vibrio furnissii ORGANISM Vibrio furnissii Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Vibrionales; Vibrionaceae; Vibrio. REFERENCE 1 (residues 1 to 324) AUTHORS Simm,R., Fetherston,J.D., Kader,A., Romling,U. and Perry,R.D. TITLE Phenotypic convergence mediated by GGDEF-domain-containing proteins JOURNAL J Bacteriol 187 (19), 6816-6823 (2005) PUBMED 16166544 REMARK Erratum:[J Bacteriol. 2006 Mar;188(5):2024] REFERENCE 2 (residues 1 to 324) AUTHORS Aravind,L. and Ponting,C.P. TITLE The GAF domain: an evolutionary link between diverse phototransducing proteins JOURNAL Trends Biochem Sci 22 (12), 458-459 (1997) PUBMED 9433123 COMMENT REFSEQ: This record represents a single, non-redundant, protein sequence which may be annotated on many different RefSeq genomes from the same, or different, species. ##Evidence-For-Name-Assignment-START## Evidence Category :: Conserved Domain (CDD) Evidence Accession :: Domain architecture ID 13413304 Evidence Source :: NCBI SPARCLE ##Evidence-For-Name-Assignment-END## COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..324 /organism="Vibrio furnissii" /db_xref="taxon:29494" Protein 1..324 /product="sensor domain-containing diguanylate cyclase" /EC_number="2.7.7.65" /GO_component="GO:0005886 - plasma membrane [Evidence IEA]" /GO_function="GO:0005515 - protein binding [Evidence IEA]" /GO_function="GO:0005525 - GTP binding [Evidence IEA]" /GO_function="GO:0046872 - metal ion binding [Evidence IEA]" /GO_function="GO:0052621 - diguanylate cyclase activity [Evidence IEA]" /GO_process="GO:0007165 - signal transduction [Evidence IEA]" /calculated_mol_wt=36370 Region 8..>317 /region_name="COG5001" /note="Cyclic di-GMP metabolism protein, combines GGDEF and EAL domains with a 6TM membrane domain [Signal transduction mechanisms]" /db_xref="CDD:444025" Region 167..319 /region_name="GGDEF" /note="Diguanylate-cyclase (DGC) or GGDEF domain; cd01949" /db_xref="CDD:143635" Site order(202,245) /site_type="metal-binding" /note="metal binding site [ion binding]" /db_xref="CDD:143635" Site order(207,210..211,215,219,241,243..246) /site_type="active" /db_xref="CDD:143635" Site order(237,265) /site_type="active" /note="I-site [active]" /db_xref="CDD:143635" ORIGIN 1 mqkpakpide qqriaslhkl gildsapeer fdrvtrlarr lfdvpialvt lvdekrqwfk 61 ssfglnvset prdisfcgha ilgdepfiin navaderfad nplvtdnphi rfyagvplvf 121 qdgsklgtlc iidteprnln hdeiidlldl akmaerelaa thnasvdelt nisnrrgfls 181 lvskslmhcr fnripyclaf fdlngfkain dqlghsvgdd alqdfaqlml ssfresdlia 241 rlggdefvvf msstldeeaq raierfrhav tefndtanrp yqlafcsgtv agdglsevhi 301 dtlleqadqv myrqksqira aktr