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sensor domain-containing diguanylate cyclase [Vibrio furnissii].


LOCUS       WP_004727256             324 aa            linear   BCT 23-DEC-2024
ACCESSION   WP_004727256
VERSION     WP_004727256.1
KEYWORDS    RefSeq.
SOURCE      Vibrio furnissii
  ORGANISM  Vibrio furnissii
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Vibrionales; Vibrionaceae; Vibrio.
REFERENCE   1  (residues 1 to 324)
  AUTHORS   Simm,R., Fetherston,J.D., Kader,A., Romling,U. and Perry,R.D.
  TITLE     Phenotypic convergence mediated by GGDEF-domain-containing proteins
  JOURNAL   J Bacteriol 187 (19), 6816-6823 (2005)
   PUBMED   16166544
  REMARK    Erratum:[J Bacteriol. 2006 Mar;188(5):2024]
REFERENCE   2  (residues 1 to 324)
  AUTHORS   Aravind,L. and Ponting,C.P.
  TITLE     The GAF domain: an evolutionary link between diverse
            phototransducing proteins
  JOURNAL   Trends Biochem Sci 22 (12), 458-459 (1997)
   PUBMED   9433123
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 13413304
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..324
                     /organism="Vibrio furnissii"
                     /db_xref="taxon:29494"
     Protein         1..324
                     /product="sensor domain-containing diguanylate cyclase"
                     /EC_number="2.7.7.65"
                     /GO_component="GO:0005886 - plasma membrane [Evidence
                     IEA]"
                     /GO_function="GO:0005515 - protein binding [Evidence IEA]"
                     /GO_function="GO:0005525 - GTP binding [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0052621 - diguanylate cyclase activity
                     [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /calculated_mol_wt=36370
     Region          8..>317
                     /region_name="COG5001"
                     /note="Cyclic di-GMP metabolism protein, combines GGDEF
                     and EAL domains with a 6TM membrane domain [Signal
                     transduction mechanisms]"
                     /db_xref="CDD:444025"
     Region          167..319
                     /region_name="GGDEF"
                     /note="Diguanylate-cyclase (DGC) or GGDEF domain; cd01949"
                     /db_xref="CDD:143635"
     Site            order(202,245)
                     /site_type="metal-binding"
                     /note="metal binding site [ion binding]"
                     /db_xref="CDD:143635"
     Site            order(207,210..211,215,219,241,243..246)
                     /site_type="active"
                     /db_xref="CDD:143635"
     Site            order(237,265)
                     /site_type="active"
                     /note="I-site [active]"
                     /db_xref="CDD:143635"
ORIGIN      
        1 mqkpakpide qqriaslhkl gildsapeer fdrvtrlarr lfdvpialvt lvdekrqwfk
       61 ssfglnvset prdisfcgha ilgdepfiin navaderfad nplvtdnphi rfyagvplvf
      121 qdgsklgtlc iidteprnln hdeiidlldl akmaerelaa thnasvdelt nisnrrgfls
      181 lvskslmhcr fnripyclaf fdlngfkain dqlghsvgdd alqdfaqlml ssfresdlia
      241 rlggdefvvf msstldeeaq raierfrhav tefndtanrp yqlafcsgtv agdglsevhi
      301 dtlleqadqv myrqksqira aktr