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efflux RND transporter periplasmic adaptor subunit [Vibrio


LOCUS       WP_004413888             381 aa            linear   BCT 24-JUL-2024
            orientalis].
ACCESSION   WP_004413888
VERSION     WP_004413888.1
KEYWORDS    RefSeq.
SOURCE      Vibrio orientalis
  ORGANISM  Vibrio orientalis
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Vibrionales; Vibrionaceae; Vibrio; Vibrio oreintalis group.
REFERENCE   1  (residues 1 to 381)
  AUTHORS   Colclough,A.L., Alav,I., Whittle,E.E., Pugh,H.L., Darby,E.M.,
            Legood,S.W., McNeil,H.E. and Blair,J.M.
  TITLE     RND efflux pumps in Gram-negative bacteria; regulation, structure
            and role in antibiotic resistance
  JOURNAL   Future Microbiol 15, 143-157 (2020)
   PUBMED   32073314
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11436533
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..381
                     /organism="Vibrio orientalis"
                     /db_xref="taxon:28175"
     Protein         1..381
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_function="GO:0042802 - identical protein binding
                     [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=41507
     Region          48..378
                     /region_name="AcrA"
                     /note="Multidrug efflux pump subunit AcrA (membrane-fusion
                     protein) [Cell wall/membrane/envelope biogenesis, Defense
                     mechanisms]; COG0845"
                     /db_xref="CDD:440606"
ORIGIN      
        1 mttkplrwll pfiilggaya gysaiassap esletkppka ppivkvskvs ssdhkvvits
       61 hgelqpvevt qlsaqvsgev lswhpnfvvg givkrgevlf slesdnyqaa vlqaeaqlag
      121 aqaalieeea raevakrqak klpqkqvtdl ylrkpqllsa yaqvksalae lkrakrdlan
      181 ckvvapydal vvardigvgq fvsagahvat lnnveageih ipiagfdsaf lpqdyagtsa
      241 qviqrgient yrdgvidrdl gvidsstrmi nmvvkvdnpy aiesdqapmk fgsyvevqfs
      301 gkelkhiyrl pqelvnnrqv wvvnsdnqle prtvnvlrae kefmlinqgl sdddqivltv
      361 peypqtglqv evavqdsqld k