efflux RND transporter permease subunit [Vibrio metschnikovii].

LOCUS       WP_004395135            1024 aa            linear   BCT 01-JAN-2025
ACCESSION   WP_004395135
VERSION     WP_004395135.1
KEYWORDS    RefSeq.
SOURCE      Vibrio metschnikovii
  ORGANISM  Vibrio metschnikovii
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Vibrionales; Vibrionaceae; Vibrio.
REFERENCE   1  (residues 1 to 1024)
  AUTHORS   Nikaido,H. and Takatsuka,Y.
  TITLE     Mechanisms of RND multidrug efflux pumps
  JOURNAL   Biochim Biophys Acta 1794 (5), 769-781 (2009)
   PUBMED   19026770
REFERENCE   2  (residues 1 to 1024)
  AUTHORS   Tseng,T.T., Gratwick,K.S., Kollman,J., Park,D., Nies,D.H.,
            Goffeau,A. and Saier,M.H. Jr.
  TITLE     The RND permease superfamily: an ancient, ubiquitous and diverse
            family that includes human disease and development proteins
  JOURNAL   J Mol Microbiol Biotechnol 1 (1), 107-125 (1999)
   PUBMED   10941792
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11436314
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..1024
                     /organism="Vibrio metschnikovii"
                     /db_xref="taxon:28172"
     Protein         1..1024
                     /product="efflux RND transporter permease subunit"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015562 - efflux transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0042908 - xenobiotic transport [Evidence
                     IEA]"
                     /calculated_mol_wt=110916
     Region          1..1011
                     /region_name="AcrB"
                     /note="Multidrug efflux pump subunit AcrB [Defense
                     mechanisms]; COG0841"
                     /db_xref="CDD:440603"
ORIGIN      
        1 mrftdvfikk pilasvvslf iillglraim dmnvrqfpei qnavisvstt yvgadadliq
       61 gfittplere iaaaegidyl vstsvagnst ieaylrldyd pnqaltqiaa qvnkvrselp
      121 enarepvvtl kvgesvaamy lafysevlgd nqitdylvrv vepqlstipg vqraeilgar
      181 tfamrvwlds vkmaaygltg sdvatalrsn nvlaalgrtk gqmvaidlta atdlrdveef
      241 kqlvvssdgq svvrladvae velgaenyes svsfnglaat figievspda naldviadvr
      301 qvwdqdiipq lpqglsayia ydsteyiena idevvmsiil alaivvfviy aflgsfrsvi
      361 ipavaipvsl igtfflmwll gfsinlltll amvlaigvvv ddaiimleni hrhieegksr
      421 idaaiqgare lawpiitmst tlvavflpig fvggltgvlf vefaftlaas vilsgivalt
      481 lspvmcayil kphssdnkke ksleqwldkq fdrlhhsyqr tlhslldsks vvltfgaivl
      541 vscyflfits pseleppedq gfvfsilesd syhtldaltk streldrlvd dveeienvfi
      601 inglggtnta iagivlapwe rrdrlthdvl akdiqpflaq qpglnsfalv ppslpspggg
      661 tpvefiigst qpfealqevv qeilgramas grfifvdsdl kinrprqtve vdrekaalmg
      721 vsmqqiaadl gsllsgadtg rfsldnrsyr vipqverser lnpdqltnyy trnqqgelvp
      781 lsalvtlses vqpqalrgfq qlnavkisgv prpgvplgea lavldniaae vmpagfsvdy
      841 sgqsrqykse gqqlvvtfff aliviflila aqfesfknai iimvtvpmsv cgaliftslg
      901 ftsiniytqv glltlvglia khgilivefa nqlqmdgksk rdaieeatai rlrpilmtta
      961 atvlamipll iatgagagsr yamglviasg msigtlftlf vvpamyllla kdlhqgqves
     1021 easa