bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP

LOCUS       WP_004395074             211 aa            linear   BCT 13-OCT-2021
            diphosphatase HisIE [Vibrio metschnikovii].
ACCESSION   WP_004395074
VERSION     WP_004395074.1
KEYWORDS    RefSeq.
SOURCE      Vibrio metschnikovii
  ORGANISM  Vibrio metschnikovii
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Vibrionales; Vibrionaceae; Vibrio.
REFERENCE   1  (residues 1 to 211)
  AUTHORS   Carlomagno,M.S., Chiariotti,L., Alifano,P., Nappo,A.G. and
            Bruni,C.B.
  TITLE     Structure and function of the Salmonella typhimurium and
            Escherichia coli K-12 histidine operons
  JOURNAL   J Mol Biol 203 (3), 585-606 (1988)
   PUBMED   3062174
REFERENCE   2  (residues 1 to 211)
  AUTHORS   Bruni,C.B., Carlomagno,M.S., Formisano,S. and Paolella,G.
  TITLE     Primary and secondary structural homologies between the HIS4 gene
            product of Saccharomyces cerevisiae and the hisIE and hisD gene
            products of Escherichia coli and Salmonella typhimurium
  JOURNAL   Mol Gen Genet 203 (3), 389-396 (1986)
   PUBMED   3528746
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF002747.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK02759
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..211
                     /organism="Vibrio metschnikovii"
                     /db_xref="taxon:28172"
     gene            1..211
                     /gene="hisIE"
     Protein         1..211
                     /product="bifunctional phosphoribosyl-AMP
                     cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE"
                     /EC_number="3.5.4.19"
                     /EC_number="3.6.1.31"
                     /GO_function="GO:0004635 - phosphoribosyl-AMP
                     cyclohydrolase activity [Evidence IEA]"
                     /GO_function="GO:0004636 - phosphoribosyl-ATP
                     diphosphatase activity [Evidence IEA]"
                     /GO_process="GO:0000105 - histidine biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=23327
     Region          11..210
                     /region_name="PRK02759"
                     /note="bifunctional phosphoribosyl-AMP
                     cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE"
                     /db_xref="CDD:235067"
ORIGIN      
        1 msqtkqterp lveridwqkv dglipaivqd fdssqvlmmg ymnpealevt lttkqvtfys
       61 rskqrlwtkg etsghvlqlr nlaldcdqdt llvkvnpigp tchtgtttcw dgdsqeesqm
      121 vwlhqleqll aarqsadpes sytaslyasg tkriaqkvge egvevalaaa tgdkaelise
      181 sadliyhllv llqdqglals dvidklkqrh q