M48 family metallopeptidase [Klebsiella pneumoniae].

LOCUS       WP_004229472             231 aa            linear   BCT 21-MAR-2023
ACCESSION   WP_004229472
VERSION     WP_004229472.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group;
            Klebsiella; Klebsiella pneumoniae complex.
REFERENCE   1  (residues 1 to 231)
  AUTHORS   Soltes,G.R., Martin,N.R., Park,E., Sutterlin,H.A. and Silhavy,T.J.
  TITLE     Distinctive Roles for Periplasmic Proteases in the Maintenance of
            Essential Outer Membrane Protein Assembly
  JOURNAL   J Bacteriol 199 (20), e00418-17 (2017)
   PUBMED   28784813
  REMARK    Publication Status: Online-Only
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11574521
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..231
                     /organism="Klebsiella pneumoniae"
                     /db_xref="taxon:573"
     Protein         1..231
                     /product="M48 family metallopeptidase"
                     /EC_number="3.4.-.-"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0004222 - metalloendopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0008237 - metallopeptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /calculated_mol_wt=24573
     Region          9..224
                     /region_name="M48C_loiP_like"
                     /note="Peptidase M48C Ste24p loiP-like, integral membrane
                     protein; cd07334"
                     /db_xref="CDD:320693"
     Site            order(109..110,113,168,172,211)
                     /site_type="active"
                     /note="putative active site [active]"
                     /db_xref="CDD:320693"
     Site            order(109,113,168,211)
                     /site_type="other"
                     /note="Zn binding site [ion binding]"
                     /db_xref="CDD:320693"
ORIGIN      
        1 mdsngllssg aeafqaysls daqvktlsdq ackemdakak iapanseysq rlnkiaaalg
       61 dningqpvny kvyetkdvna famangcirv ysglmdlmnd neveavighe mghvalghvk
      121 kgmqvalgtn avraaaasag givgslsqsq lgdlgeklvn sqfsqrqese addysydllr
      181 krginpsgla tsfeklakle agrqssmfdd hpasearaqh irdrmkadgi k