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dipeptide ABC transporter periplasmic-binding protein DppA


LOCUS       WP_004228767             526 aa            linear   BCT 29-OCT-2023
            [Klebsiella pneumoniae].
ACCESSION   WP_004228767
VERSION     WP_004228767.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group;
            Klebsiella; Klebsiella pneumoniae complex.
REFERENCE   1  (residues 1 to 526)
  AUTHORS   Letoffe,S., Delepelaire,P. and Wandersman,C.
  TITLE     The housekeeping dipeptide permease is the Escherichia coli heme
            transporter and functions with two optional peptide binding
            proteins
  JOURNAL   Proc Natl Acad Sci U S A 103 (34), 12891-12896 (2006)
   PUBMED   16905647
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF043070.1
            Evidence Source    :: NCBIFAM
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..526
                     /organism="Klebsiella pneumoniae"
                     /db_xref="taxon:573"
     gene            1..526
                     /gene="dppA"
                     /GO_component="GO:0055052 - ATP-binding cassette (ABC)
                     transporter complex, substrate-binding subunit-containing
                     [Evidence IEA]"
                     /GO_function="GO:0042626 - ATPase-coupled transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0140359 - ABC-type transporter activity
                     [Evidence IEA]"
     Protein         1..526
                     /product="dipeptide ABC transporter periplasmic-binding
                     protein DppA"
                     /EC_number="7.4.2.9"
                     /GO_component="GO:0030288 - outer membrane-bounded
                     periplasmic space [Evidence IEA]"
                     /GO_function="GO:0071916 - dipeptide transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0042938 - dipeptide transport [Evidence
                     IEA]"
                     /calculated_mol_wt=59081
     Region          21..510
                     /region_name="PBP2_DppA_like"
                     /note="The substrate-binding component of an ABC-type
                     dipeptide import system contains the type 2 periplasmic
                     binding fold; cd08493"
                     /db_xref="CDD:173858"
     Site            order(405,409,422..425,427)
                     /site_type="other"
                     /note="peptide binding site [polypeptide binding]"
                     /db_xref="CDD:173858"
ORIGIN      
        1 mlklglslva mtvaasvqak tlvycsegsp egfnpqlfts gttydassvp iynrlvefkt
       61 gttevipgla ekwevsadgk tytfhlrqgv kwqdnkdfkp trdlnaddvv fsfdrqkntn
      121 npyhkvsggs yeyfegmglp dlisevkkvd dntvqfvltr peapfladla mdfasilske
      181 yadnmlkagt pekvdlnpig tgpfqllqyq kdsrilykaf pgywgtkpki drlvfsitpd
      241 asvryaklqk necqvmpypn padiarmked knitlleqpg lnvgylsfnt ekkplddvkv
      301 rqaltyavnk eaiikavyqg agqaaknlip ptmwgynddv kdytydpeka kqllkeagle
      361 kgftidlwam pvqrpynpna rrmaemiqad wakigvqaki vtyewgeylk rakagehqsv
      421 mmgwtgdngd pdnffatlfs caaakdgsny srwcykpfed liqparatdd hnkrielykq
      481 aqvvmhdqap aliiahstvy epvrkevkgy vvdplgkhhf dnvsve