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LacI family DNA-binding transcriptional regulator [Klebsiella


LOCUS       WP_004226803             300 aa            linear   BCT 22-JUL-2024
            pneumoniae].
ACCESSION   WP_004226803
VERSION     WP_004226803.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group;
            Klebsiella; Klebsiella pneumoniae complex.
REFERENCE   1  (residues 1 to 300)
  AUTHORS   Fukami-Kobayashi,K., Tateno,Y. and Nishikawa,K.
  TITLE     Parallel evolution of ligand specificity between LacI/GalR family
            repressors and periplasmic sugar-binding proteins
  JOURNAL   Mol Biol Evol 20 (2), 267-277 (2003)
   PUBMED   12598694
REFERENCE   2  (residues 1 to 300)
  AUTHORS   Nguyen,C.C. and Saier,M.H. Jr.
  TITLE     Phylogenetic, structural and functional analyses of the LacI-GalR
            family of bacterial transcription factors
  JOURNAL   FEBS Lett 377 (2), 98-102 (1995)
   PUBMED   8543068
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11446715
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..300
                     /organism="Klebsiella pneumoniae"
                     /db_xref="taxon:573"
     Protein         1..300
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription
                     factor activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /calculated_mol_wt=32792
     Region          2..297
                     /region_name="PurR"
                     /note="DNA-binding transcriptional regulator, LacI/PurR
                     family [Transcription]; COG1609"
                     /db_xref="CDD:441217"
ORIGIN      
        1 mltgtrgvre esreavlrav eelnyrpsfa aqnlasqtss hvglvisaqd eshgarllpl
       61 lsqalkglnk sllvqyvsdp veqaaviddl qrqcvavvvl gavaadaprn viafdrfgva
      121 gsnsqgydfa fatesacryv igkghrnial lvdsdsddas rqmlegyrnv lqnysipfnr
      181 qlvltanddv eqalltlins fskysviivk rdryaaeamr llreftiavp qevsllsled
      241 splasllypp ltciswplea lldnciqrir sliddrptft aegrslagrl iprqsvadis