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MULTISPECIES: LysR substrate-binding domain-containing protein


LOCUS       WP_004221441             320 aa            linear   BCT 02-MAR-2025
            [Klebsiella].
ACCESSION   WP_004221441
VERSION     WP_004221441.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 320)
  AUTHORS   Tyrrell,R., Verschueren,K.H., Dodson,E.J., Murshudov,G.N., Addy,C.
            and Wilkinson,A.J.
  TITLE     The structure of the cofactor-binding fragment of the LysR family
            member, CysB: a familiar fold with a surprising subunit arrangement
  JOURNAL   Structure 5 (8), 1017-1032 (1997)
   PUBMED   9309218
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF015431.6
            Evidence Source    :: EMBL-EBI
            Source Identifier  :: PF03466.25
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..320
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..320
                     /product="LysR substrate-binding domain-containing
                     protein"
                     /calculated_mol_wt=36011
     Region          9..>163
                     /region_name="rbcR"
                     /note="LysR transcriptional regulator; Provisional;
                     CHL00180"
                     /db_xref="CDD:177082"
     Region          102..298
                     /region_name="PBP2_CrgA_like_9"
                     /note="The C-terminal substrate binding domain of an
                     uncharacterized LysR-type transcriptional regulator
                     CrgA-like, contains the type 2 periplasmic binding fold;
                     cd08479"
                     /db_xref="CDD:176168"
     Site            order(112,116,155,169,171,234,251,277)
                     /site_type="active"
                     /note="putative effector binding pocket [active]"
                     /db_xref="CDD:176168"
     Site            order(113..114,118..119,121..122,125,129,131..137,198,
                     228..232,239..240,243)
                     /site_type="other"
                     /note="putative dimerization interface [polypeptide
                     binding]"
                     /db_xref="CDD:176168"
ORIGIN      
        1 mkhktqimnn lpllndlrvf mlvarragfa aaaeelgvsp afvskrvsll eqtlnvmllh
       61 rttrrvtite egeriyewaq rilqdvdemm delsdvrqvp qgtlriissf gfgrrvvapa
      121 lsalalqypq lelrfdvqdr lvdlvnegvd ldirvgddia pnliarqlaa nhrvlcaspq
      181 flarhappkq lsdlaalpcl vikerdhpfg vwqlhskegq haikvtgpls snhgeivhqw
      241 cldgqgialr swwdvrenia sghlvqvlpd ywqpanvwav yvsrlatsak irttveflrh
      301 yfqlhypqhe ptasavgrgd