MULTISPECIES: LacI family DNA-binding transcriptional regulator

LOCUS       WP_004219745             376 aa            linear   BCT 22-JUL-2024
            [Klebsiella].
ACCESSION   WP_004219745
VERSION     WP_004219745.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 376)
  AUTHORS   Fukami-Kobayashi,K., Tateno,Y. and Nishikawa,K.
  TITLE     Parallel evolution of ligand specificity between LacI/GalR family
            repressors and periplasmic sugar-binding proteins
  JOURNAL   Mol Biol Evol 20 (2), 267-277 (2003)
   PUBMED   12598694
REFERENCE   2  (residues 1 to 376)
  AUTHORS   Nguyen,C.C. and Saier,M.H. Jr.
  TITLE     Phylogenetic, structural and functional analyses of the LacI-GalR
            family of bacterial transcription factors
  JOURNAL   FEBS Lett 377 (2), 98-102 (1995)
   PUBMED   8543068
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11446715
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..376
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..376
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription
                     factor activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /calculated_mol_wt=41449
     Region          22..360
                     /region_name="PurR"
                     /note="DNA-binding transcriptional regulator, LacI/PurR
                     family [Transcription]; COG1609"
                     /db_xref="CDD:441217"
ORIGIN      
        1 mcfgdyensf ifqseldhkm dkklrvaeia artglspstv srvlagkant sdkarravld
       61 carelgvmqg laagrlllnh llvfapqraf dersdifyyr viqsinnala ahevrlryca
      121 ldendsdanl flarmnepet qaavllgidd phihglaadl gkpcvlincr degmrlpsia
      181 pdhrligqca arylfdmghr avmnvmclrr ytmelrlggi qeawrarnlr ftasrdlisv
      241 anfsaretee qvgawldglq grplptaflv ggdfmaagtv salqkrglrv pqdvsvmsid
      301 gfnlaaiqev pltavhvprd elgseavhll qqrllrpeap hgslllhgtl vvrdsvrrir
      361 pgkghtavep qglydd