bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase

LOCUS       WP_004219333             839 aa            linear   BCT 04-JUN-2024
            [Klebsiella pneumoniae].
ACCESSION   WP_004219333
VERSION     WP_004219333.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group;
            Klebsiella; Klebsiella pneumoniae complex.
REFERENCE   1  (residues 1 to 839)
  AUTHORS   Bradbury,A.J., Gruer,M.J., Rudd,K.E. and Guest,J.R.
  TITLE     The second aconitase (AcnB) of Escherichia coli
  JOURNAL   Microbiology (Reading) 142 (Pt 2), 389-400 (1996)
   PUBMED   8932712
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00117.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..839
                     /organism="Klebsiella pneumoniae"
                     /db_xref="taxon:573"
     gene            1..839
                     /gene="acnB"
     Protein         1..839
                     /product="bifunctional aconitate hydratase
                     2/2-methylisocitrate dehydratase"
                     /EC_number="4.2.1.3"
                     /EC_number="4.2.1.99"
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0003994 - aconitate hydratase activity
                     [Evidence IEA]"
                     /GO_function="GO:0051539 - 4 iron, 4 sulfur cluster
                     binding [Evidence IEA]"
                     /GO_process="GO:0006099 - tricarboxylic acid cycle
                     [Evidence IEA]"
                     /calculated_mol_wt=90534
     Region          1..838
                     /region_name="AcnB"
                     /note="Aconitase B [Energy production and conversion];
                     COG1049"
                     /db_xref="CDD:440670"
ORIGIN      
        1 maalvellkn ppageeefll dllinrvppg vdeaayvkag flaaiakgea tsplvtpeka
       61 vellgtmqgg ynihplidal ddaklapiaa kalshtllmf dnfydveeka kagnehakqv
      121 mqswadaewf lnrpqlaeki tvtvfkvtge tntddlspap dawsrpdipl halamlknpr
      181 egiepdqpgv vgpikqieal qqkgyplayv gdvvgtgssr ksatnsvlwf mgddipnvpn
      241 krggglclgg kiapiffntm edagalpiev dvsnlnmgdv idvypfkgev rnhetnella
      301 sfelktdvli devraggrip liigrglttk arealglphs dvfrqakdva estrgfslaq
      361 kmvgracgva girpgaycep kmtsvgsqdt tgpmtrdelk dlaclgfsad lvmqsfchta
      421 aypkpvdvtt hhtlpdfimn rggvslrpgd gvihswlnrm llpdtvgtgg dshtrfpigi
      481 sfpagsglva faaatgvmpl dmpesvlvrf kgkmqpgitl rdlvhaiply aikqglltve
      541 kkgkknifsg rileieglpd lkveqafelt dasaersaag ctiklnkepi veylnsnivl
      601 lkwmiaegyg drrtlerriq gmekwladpq lleadadaey aavididlad ikepilcapn
      661 dpddarllsd vqgekidevf igscmtnigh fraagkllds hkgqlptrlw vapptrmdaa
      721 qlteegyysv fgksgariei pgcslcmgnq arvadgatvv ststrnfpnr lgtganvyla
      781 saelaavasl lgklptpeey qtfvaqvdkt aedtyrylnf nqldqyteka dgvifqtav