MULTISPECIES: LysR family transcriptional regulator [Klebsiella].

LOCUS       WP_004218747             296 aa            linear   BCT 01-JAN-2025
ACCESSION   WP_004218747
VERSION     WP_004218747.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 296)
  AUTHORS   Maddocks,S.E. and Oyston,P.C.F.
  TITLE     Structure and function of the LysR-type transcriptional regulator
            (LTTR) family proteins
  JOURNAL   Microbiology (Reading) 154 (Pt 12), 3609-3623 (2008)
   PUBMED   19047729
REFERENCE   2  (residues 1 to 296)
  AUTHORS   Schell,M.A.
  TITLE     Molecular biology of the LysR family of transcriptional regulators
  JOURNAL   Annu Rev Microbiol 47, 597-626 (1993)
   PUBMED   8257110
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10444112
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..296
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..296
                     /product="LysR family transcriptional regulator"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription
                     factor activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /calculated_mol_wt=33165
     Region          4..63
                     /region_name="HTH_1"
                     /note="Bacterial regulatory helix-turn-helix protein, lysR
                     family; pfam00126"
                     /db_xref="CDD:459683"
     Region          91..291
                     /region_name="PBP2_CrgA_like_3"
                     /note="The C-terminal substrate binding domain of an
                     uncharacterized LysR-type transcriptional regulator
                     CrgA-like, contains the type 2 periplasmic binding fold;
                     cd08472"
                     /db_xref="CDD:176161"
     Site            order(101,105,144,158,160,224,241,268)
                     /site_type="active"
                     /note="putative effector binding pocket [active]"
                     /db_xref="CDD:176161"
     Site            order(102..103,107..108,110..111,114,118,120..126,187,
                     218..222,229..230,233)
                     /site_type="other"
                     /note="putative dimerization interface [polypeptide
                     binding]"
                     /db_xref="CDD:176161"
ORIGIN      
        1 mnlfenikif ieivdagsfa qaaenlqihr pavtkalqql eqesgvrllq rttrrlyltp
       61 egeefyrrsk pllsqaddll esfapdrpir gqlrvdmpia farllviphl pdfyqahpev
      121 eivlsssdvr rdmlrdgldc llrvgdledg dyvarslgev alttcaspgy larygapatl
      181 edlqshlavn wvnsssrqim pwrfqtpegi rqiaipgklv ldnsevftaa glaglgmlqg
      241 mrfflqpyid sgqlvevlpd fpaprrplsl lyphrhlshk vrvfadwlqg lvatld