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dethiobiotin synthase [Klebsiella pneumoniae].


LOCUS       WP_004218508             198 aa            linear   BCT 04-JUN-2024
ACCESSION   WP_004218508
VERSION     WP_004218508.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group;
            Klebsiella; Klebsiella pneumoniae complex.
REFERENCE   1  (residues 1 to 198)
  AUTHORS   Yang,G., Sandalova,T., Lohman,K., Lindqvist,Y. and Rendina,A.R.
  TITLE     Active site mutants of Escherichia coli dethiobiotin synthetase:
            effects of mutations on enzyme catalytic and structural properties
  JOURNAL   Biochemistry 36 (16), 4751-4760 (1997)
   PUBMED   9125495
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00347.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..198
                     /organism="Klebsiella pneumoniae"
                     /db_xref="taxon:573"
     gene            1..198
                     /gene="bioD"
     Protein         1..198
                     /product="dethiobiotin synthase"
                     /EC_number="6.3.3.3"
                     /GO_function="GO:0000287 - magnesium ion binding [Evidence
                     IEA]"
                     /GO_function="GO:0004141 - dethiobiotin synthase activity
                     [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0009102 - biotin biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=21289
     Region          2..185
                     /region_name="BioD"
                     /note="Dethiobiotin synthetase [Coenzyme transport and
                     metabolism]; COG0132"
                     /db_xref="CDD:439902"
ORIGIN      
        1 magykpvakg sketpdglrn kdalvlqsvs tlalpyeavn pialsedess vahscpinyg
       61 llsdglqrla aqvehvvveg tggwrslmnd lrplsewvvq eqlpvlmvvg iqegcinhal
      121 ltaqaiandg lpligwvanr inpglahyae iidvlskklp apligelpyl praeqrelsr
      181 yvdldmlgnv maidripa