peptidoglycan glycosyltransferase/peptidoglycan DD-transpeptidase

LOCUS       WP_004218297             809 aa            linear   BCT 01-JUL-2024
            MrcA [Klebsiella pneumoniae].
ACCESSION   WP_004218297
VERSION     WP_004218297.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group;
            Klebsiella; Klebsiella pneumoniae complex.
REFERENCE   1  (residues 1 to 809)
  AUTHORS   Egan,A.J., Biboy,J., van't Veer,I., Breukink,E. and Vollmer,W.
  TITLE     Activities and regulation of peptidoglycan synthases
  JOURNAL   Philos Trans R Soc Lond B Biol Sci 370 (1679) (2015)
   PUBMED   26370943
REFERENCE   2  (residues 1 to 809)
  AUTHORS   Born,P., Breukink,E. and Vollmer,W.
  TITLE     In vitro synthesis of cross-linked murein and its attachment to
            sacculi by PBP1A from Escherichia coli
  JOURNAL   J Biol Chem 281 (37), 26985-26993 (2006)
   PUBMED   16840781
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF008643.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK11636
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..809
                     /organism="Klebsiella pneumoniae"
                     /db_xref="taxon:573"
     gene            1..809
                     /gene="mrcA"
     Protein         1..809
                     /product="peptidoglycan glycosyltransferase/peptidoglycan
                     DD-transpeptidase MrcA"
                     /EC_number="2.4.99.28"
                     /EC_number="3.4.16.4"
                     /GO_function="GO:0008658 - penicillin binding [Evidence
                     IEA]"
                     /calculated_mol_wt=88526
     Region          1..809
                     /region_name="mrcA"
                     /note="penicillin-binding protein 1a; Provisional;
                     PRK11636"
                     /db_xref="CDD:183248"
ORIGIN      
        1 mqipmqvysa dgeliaqyge krripvtlqq ippelvkafi atedsrfyeh hgvdpvgifr
       61 aasvamfsgh asqgastitq qlarnfflsp ektlmrkike aflairieql lnkdeilely
      121 lnkiylgyra ygvgaaaqvy fgkpidqltl semaviaglp kapstfnply smdratarrn
      181 vvlsrmlseg yitqaqydea rsepidasyh apkiafsapy lsemvrqemv nrygeqayed
      241 gyrvyttitr knqqaaqqav rnnvldydmr hgyrgpasvl wkvgetpwet kkivdslkrq
      301 sgygplfpav vtsanaqeav allangnsvs ltmegvrwar rfisdtqqga tprkvndvvq
      361 agqqiwvrkv gdswwlsqlp dvnsalvsin pqngaiialv ggfdfnqskf nratqalrqv
      421 gsnikpflyt aamdkgltla smlndvpisr wdagagsdwr pknsppqyag pirlrqglgq
      481 sknvvmvram ramgvdyaae ylqrfgfpaq nivhteslal gsasftplqv argysvmang
      541 gflvnpffis kiendqggvl feerpkiacp qcdlpviygd tpksnvlenk dvedvatsae
      601 pqngnvppqp qleqanqslv aqsgaqeyap hvintplafl iksalnsnif gepgwmgtgw
      661 ragrdlqrhd iggktgttns skdawfsgyg pgvvtsvwig fddhrrdlgr ttasgaikdq
      721 isgyeggaks aqpawdsfmk svlegvpeep ltpppgivtv nidrstgqla nggnsraeyf
      781 iegtqptqqa vrevgttltd gggethelf