tRNA dihydrouridine synthase DusB [Klebsiella pneumoniae].

LOCUS       WP_004218262             290 aa            linear   BCT 01-JUL-2024
ACCESSION   WP_004218262
VERSION     WP_004218262.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group;
            Klebsiella; Klebsiella pneumoniae complex.
REFERENCE   1  (residues 1 to 290)
  AUTHORS   Morett,E. and Bork,P.
  TITLE     Evolution of new protein function: recombinational enhancer Fis
            originated by horizontal gene transfer from the transcriptional
            regulator NtrC
  JOURNAL   FEBS Lett 433 (1-2), 108-112 (1998)
   PUBMED   9738943
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR00737.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..290
                     /organism="Klebsiella pneumoniae"
                     /db_xref="taxon:573"
     gene            1..290
                     /gene="dusB"
     Protein         1..290
                     /product="tRNA dihydrouridine synthase DusB"
                     /EC_number="1.3.1.-"
                     /GO_function="GO:0017150 - tRNA dihydrouridine synthase
                     activity [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /GO_process="GO:0008033 - tRNA processing [Evidence IEA]"
                     /calculated_mol_wt=32084
     Region          1..290
                     /region_name="TIM-like beta/alpha barrel domains"
                     /note="A large family of domains similar to triose
                     phosphate isomerase (TIM) which, in general, share an
                     eight beta/alpha closed barrel structure; cl21457"
                     /db_xref="CDD:473867"
     Site            order(39,69..70,108,110,137..138,140..141,170..171,194)
                     /site_type="active"
                     /db_xref="CDD:239200"
     Site            order(69,110,138,140)
                     /site_type="active"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:239200"
     Site            order(70,108,137,141,170..171)
                     /site_type="other"
                     /note="substrate binding site [chemical binding]"
                     /db_xref="CDD:239200"
ORIGIN      
        1 mgagltvsem mssnpqvwes dksrlrmvhi depgirtvqi agsvpeemaa aarinvesga
       61 qiidinmgcp akkvnrklag sallqypdqv ksiltavvna vdvpvtlkir tgwepehrnc
      121 veiaqlaeec giqaltihgr traclfngda eydsiravkq kvsipiiang ditdplkara
      181 vldytgadal migraaqgrp wifreiqhyl dtgellpplp laevkrllca hvrelhdfyg
      241 qakgyriark hvswylqeha pddqfrrtfn aiedaseqle aleayfenfa