MULTISPECIES: MFS transporter [Klebsiella].

LOCUS       WP_004218007             400 aa            linear   BCT 31-DEC-2024
ACCESSION   WP_004218007
VERSION     WP_004218007.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 400)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 400)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
REFERENCE   3  (residues 1 to 400)
  AUTHORS   Yan,N.
  TITLE     Structural advances for the major facilitator superfamily (MFS)
            transporters
  JOURNAL   Trends Biochem Sci 38 (3), 151-159 (2013)
   PUBMED   23403214
REFERENCE   4  (residues 1 to 400)
  AUTHORS   Pao,S.S., Paulsen,I.T. and Saier,M.H. Jr.
  TITLE     Major facilitator superfamily
  JOURNAL   Microbiol Mol Biol Rev 62 (1), 1-34 (1998)
   PUBMED   9529885
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11457990
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..400
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..400
                     /product="MFS transporter"
                     /GO_component="GO:0005886 - plasma membrane [Evidence
                     IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=41608
     Region          3..364
                     /region_name="nepI"
                     /note="purine ribonucleoside efflux pump NepI; PRK10213"
                     /db_xref="CDD:182309"
ORIGIN      
        1 msalghtrah wsgvlamtlc vfvliasefm pvslltpiag dlhiteglag qgialsgala
       61 vltsltisrl tgsldrkwll lgltalmaas gviialassf pvymlgrali giviggfwsm
      121 saatairlvp qrqvpralai fnggnalatv vaaplgsylg atvgwrgafl ylvplavlaf
      181 vwqcislpsm ksprapqrqg svlrlfrlst lslgllacgl ffmgqftlft yvrpfletvt
      241 qvspsglsli lltmgiagfi gtllittvln arfyptlvai pllmaaiagt lllaghhtgs
      301 vavllslwgl lataaptgww twiartlped aetggglmva viqlsialgs tvgglvfdsl
      361 gwhstfalsg llllgaaggt fllsvkirss qrtainelna