NADPH-dependent assimilatory sulfite reductase flavoprotein subunit

LOCUS       WP_004217558             590 aa            linear   BCT 18-JUN-2019
            [Klebsiella pneumoniae].
ACCESSION   WP_004217558
VERSION     WP_004217558.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group;
            Klebsiella; Klebsiella pneumoniae complex.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF008197.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK10953
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..590
                     /organism="Klebsiella pneumoniae"
                     /db_xref="taxon:573"
     gene            1..590
                     /gene="cysJ"
     Protein         1..590
                     /product="NADPH-dependent assimilatory sulfite reductase
                     flavoprotein subunit"
                     /EC_number="1.8.1.2"
                     /GO_function="GO:0004783 - sulfite reductase (NADPH)
                     activity [Evidence IEA]"
                     /GO_function="GO:0010181 - FMN binding [Evidence IEA]"
                     /GO_function="GO:0050660 - flavin adenine dinucleotide
                     binding [Evidence IEA]"
                     /GO_process="GO:0000103 - sulfate assimilation [Evidence
                     IEA]"
                     /GO_process="GO:0019344 - cysteine biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=64979
     Region          1..590
                     /region_name="cysJ"
                     /note="NADPH-dependent assimilatory sulfite reductase
                     flavoprotein subunit; PRK10953"
                     /db_xref="CDD:182862"
     Site            order(266,377..380,395,397,410..413)
                     /site_type="other"
                     /note="FAD binding pocket [chemical binding]"
                     /db_xref="CDD:99796"
     Site            order(377,379..380)
                     /site_type="other"
                     /note="FAD binding motif [chemical binding]"
                     /db_xref="CDD:99796"
     Site            order(380,543,588,590)
                     /site_type="active"
                     /note="catalytic residues [active]"
                     /db_xref="CDD:99796"
     Site            order(397..400,451,453,480..481,510..511,518,520,549)
                     /site_type="other"
                     /note="NAD binding pocket [chemical binding]"
                     /db_xref="CDD:99796"
     Site            order(410,413,416)
                     /site_type="other"
                     /note="phosphate binding motif [ion binding]"
                     /db_xref="CDD:99796"
     Site            order(448,452..455,457)
                     /site_type="other"
                     /note="beta-alpha-beta structure motif"
                     /db_xref="CDD:99796"
ORIGIN      
        1 mlplnpeqla rlqaattdft ptqlawvsgy fwgvlnqqsg aavaapapaa evptitlisa
       61 sqtgnarrva ealrddllaa klnvklvnag dykfkqiaae kllvvvtstq gegeppeeav
      121 alhkflfskk apkldgtafa vfglgdtsye ffcqsgkdfd nklaelgaer lldrvdadve
      181 yqaaaaewra rvvealkara pvaapaqlat sgavndihts pytkeaplta tlsvnqkitg
      241 rnsekdvrhi eidlgdsglr yqpgdalgvw yqndpqlvke lvellwlkgd epvtvegktl
      301 plsealqwhf eltvntativ enyatltrse sllplvgdka qlqqyaaatp ivdmvrfspa
      361 qldaealigl lrpltprlys iassqaeves evhvtvgvvr yeiegrarag gassfladrv
      421 eedgevrvfi ehndnfrlpa npetpvimig pgtgiapfra fmqqraadga qgknwlffgn
      481 phftedflyq vewqsyvkeg lltridlaws rdqqqkiyvq dklreqgael wrwindgahi
      541 yvcgdanrma kdventllev iaeygamdae aadeflselr verryqrdvy