MULTISPECIES: S66 family peptidase [Klebsiella].

LOCUS       WP_004200181             345 aa            linear   BCT 17-FEB-2025
ACCESSION   WP_004200181
VERSION     WP_004200181.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 345)
  AUTHORS   Nocek,B., Tikhonov,A., Babnigg,G., Gu,M., Zhou,M., Makarova,K.S.,
            Vondenhoff,G., Van Aerschot,A., Kwon,K., Anderson,W.F.,
            Severinov,K. and Joachimiak,A.
  TITLE     Structural and functional characterization of microcin C resistance
            peptidase MccF from Bacillus anthracis
  JOURNAL   J Mol Biol 420 (4-5), 366-383 (2012)
   PUBMED   22516613
REFERENCE   2  (residues 1 to 345)
  AUTHORS   Korza,H.J. and Bochtler,M.
  TITLE     Pseudomonas aeruginosa LD-carboxypeptidase, a serine peptidase with
            a Ser-His-Glu triad and a nucleophilic elbow
  JOURNAL   J Biol Chem 280 (49), 40802-40812 (2005)
   PUBMED   16162494
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10162601
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..345
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..345
                     /product="S66 family peptidase"
                     /EC_number="3.4.-.-"
                     /GO_function="GO:0008236 - serine-type peptidase activity
                     [Evidence IEA]"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_process="GO:0006508 - proteolysis [Evidence IEA]"
                     /calculated_mol_wt=37725
     Region          13..332
                     /region_name="Peptidase_S66_mccF_like"
                     /note="Microcin C7 self-immunity protein determines
                     resistance to exogenous microcin C7; cd07062"
                     /db_xref="CDD:132883"
     Site            order(92..93,221..222,224..225,255..256,258..259,262..263,
                     300..301)
                     /site_type="other"
                     /note="putative dimer interface [polypeptide binding]"
                     /db_xref="CDD:132883"
     Site            order(115,248,317)
                     /site_type="active"
                     /note="catalytic triad [active]"
                     /db_xref="CDD:132883"
ORIGIN      
        1 msvlfpprla pgdvigvtap sagvpehlhp rlelaiknlk krgyqvregr clrsqhknks
       61 atkfsrveel msyltdpdik avmppwggdl amelldlidf dllsrskpkw fvgfsdlstl
      121 hfplttisgw atlhgpnlmd lgaqkldatt qavweilesn rgtvikqyss tafqadenqw
      181 gtasdggfnl tqktqwkrld gvtssltfsg kliggcleii srlagtpfgn vplfkasnsp
      241 qgiilyfenv emapceltra lfslrlqgwf dnlngvligr saapdvsdpt khnyldalka
      301 afeniavpvl ydvdighipp qislvngada tvffaengsw vtqql