MULTISPECIES: carboxylesterase/lipase family protein [Klebsiella].

LOCUS       WP_004200105             501 aa            linear   BCT 31-DEC-2024
ACCESSION   WP_004200105
VERSION     WP_004200105.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 501)
  AUTHORS   Fojan,P., Jonson,P.H., Petersen,M.T. and Petersen,S.B.
  TITLE     What distinguishes an esterase from a lipase: a novel structural
            approach
  JOURNAL   Biochimie 82 (11), 1033-1041 (2000)
   PUBMED   11099800
REFERENCE   2  (residues 1 to 501)
  AUTHORS   Anthonsen,H.W., Baptista,A., Drablos,F., Martel,P., Petersen,S.B.,
            Sebastiao,M. and Vaz,L.
  TITLE     Lipases and esterases: a review of their sequences, structure and
            evolution
  JOURNAL   Biotechnol Annu Rev 1, 315-371 (1995)
   PUBMED   9704093
REFERENCE   3  (residues 1 to 501)
  AUTHORS   Cygler,M., Schrag,J.D., Sussman,J.L., Harel,M., Silman,I.,
            Gentry,M.K. and Doctor,B.P.
  TITLE     Relationship between sequence conservation and three-dimensional
            structure in a large family of esterases, lipases, and related
            proteins
  JOURNAL   Protein Sci 2 (3), 366-382 (1993)
   PUBMED   8453375
REFERENCE   4  (residues 1 to 501)
  AUTHORS   Myers,M., Richmond,R.C. and Oakeshott,J.G.
  TITLE     On the origins of esterases
  JOURNAL   Mol Biol Evol 5 (2), 113-119 (1988)
   PUBMED   3163407
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10006294
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..501
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..501
                     /product="carboxylesterase/lipase family protein"
                     /EC_number="3.1.1.-"
                     /GO_function="GO:0016298 - lipase activity [Evidence IEA]"
                     /GO_function="GO:0052689 - carboxylic ester hydrolase
                     activity [Evidence IEA]"
                     /calculated_mol_wt=54943
     Region          1..494
                     /region_name="PnbA"
                     /note="Carboxylesterase type B [Lipid transport and
                     metabolism]; COG2272"
                     /db_xref="CDD:441873"
ORIGIN      
        1 mqhpskplak trqgtlagsa eqgihiwrgi pyaappvgpl rwrapqpaar wqgvrpaetf
       61 saaswqdidy crelgggdpg afsedclyln vwapasaaqp lpvmvwlhgg gftigagslp
      121 pydgkalasr dvvvvtvnyr lghlgffshp aleeeagerl ynfalldqia alqwvqenih
      181 afggdaanvt lfgesagars vlslmaspka kglfhkaiiq sgytlpdlpr ekalekgrll
      241 aehfalpqas aeelraipae afwsltapln tgpapiagda vlpqpmletf fagrqhpipv
      301 migsnsdeas vmavfgvdia gqiqklrrer rlglglikll ypgvkgdeal grevcrdmaf
      361 ttlgyvvmqa qqrvgqpcwr ywfdyvaeae hdayphgawh gnevpyvfdn lrltdpvrqy
      421 aseadlafaa qvadywaqfa rlasgeqtls gavrwpaclr grdrllrigl hkragfkven
      481 rfmrarlalf rrvmkhhvtl e