MFS transporter [Klebsiella pneumoniae].

LOCUS       WP_004200073             427 aa            linear   BCT 01-JAN-2025
ACCESSION   WP_004200073
VERSION     WP_004200073.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group;
            Klebsiella; Klebsiella pneumoniae complex.
REFERENCE   1  (residues 1 to 427)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 427)
  AUTHORS   Zhang,X.C., Zhao,Y., Heng,J. and Jiang,D.
  TITLE     Energy coupling mechanisms of MFS transporters
  JOURNAL   Protein Sci 24 (10), 1560-1579 (2015)
   PUBMED   26234418
REFERENCE   3  (residues 1 to 427)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
REFERENCE   4  (residues 1 to 427)
  AUTHORS   Yan,N.
  TITLE     Structural advances for the major facilitator superfamily (MFS)
            transporters
  JOURNAL   Trends Biochem Sci 38 (3), 151-159 (2013)
   PUBMED   23403214
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11454559
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..427
                     /organism="Klebsiella pneumoniae"
                     /db_xref="taxon:573"
     Protein         1..427
                     /product="MFS transporter"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015293 - symporter activity [Evidence
                     IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0008643 - carbohydrate transport [Evidence
                     IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=46183
     Region          1..408
                     /region_name="gph"
                     /note="sugar (Glycoside-Pentoside-Hexuronide) transporter;
                     TIGR00792"
                     /db_xref="CDD:273270"
ORIGIN      
        1 mffytdvmgl payyvglmfl vtrlvdgvad vlmglvidnt ttrwgrcrpw lligalpfgl
       61 lcilafyvpd fgttgkllya fvtylclsfl ytlvnipfca mlpfltsdsa erttlsavri
      121 llgslgativ avatlplvgm lgkgnqqqgf lytavifgvl aaffllvsfr nveekitltg
      181 ermtlkrawi slranrpwwv fasniflmwg afffqtgalv yffhyyvgnt eltaviagis
      241 tfvpllgtlt vpllarrmkk rhvylvasav nllgmgimmv sgahvlgliv gavilslgag
      301 qrtaiyfsmq adpvdygvwk tgintagilt singflgkva magagaitgv llsssgyian
      361 htqsdsalla ikacylyipa llilasmlwm grfyrlddqy eqiradldag rgaspapapt
      421 agespam