MULTISPECIES: LysR family transcriptional regulator [Klebsiella].

LOCUS       WP_004200027             297 aa            linear   BCT 01-JAN-2025
ACCESSION   WP_004200027
VERSION     WP_004200027.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 297)
  AUTHORS   Maddocks,S.E. and Oyston,P.C.F.
  TITLE     Structure and function of the LysR-type transcriptional regulator
            (LTTR) family proteins
  JOURNAL   Microbiology (Reading) 154 (Pt 12), 3609-3623 (2008)
   PUBMED   19047729
REFERENCE   2  (residues 1 to 297)
  AUTHORS   Schell,M.A.
  TITLE     Molecular biology of the LysR family of transcriptional regulators
  JOURNAL   Annu Rev Microbiol 47, 597-626 (1993)
   PUBMED   8257110
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10444056
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..297
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..297
                     /product="LysR family transcriptional regulator"
                     /GO_component="GO:0032993 - protein-DNA complex [Evidence
                     IEA]"
                     /GO_function="GO:0001216 - DNA-binding transcription
                     activator activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of DNA-templated
                     transcription [Evidence IEA]"
                     /calculated_mol_wt=32433
     Region          8..63
                     /region_name="HTH_1"
                     /note="Bacterial regulatory helix-turn-helix protein, lysR
                     family; pfam00126"
                     /db_xref="CDD:459683"
     Region          90..286
                     /region_name="PBP2_CrgA_like"
                     /note="The C-terminal substrate binding domain of
                     LysR-type transcriptional regulator CrgA and its related
                     homologs, contains the type 2 periplasmic binding domain;
                     cd08422"
                     /db_xref="CDD:176114"
     Site            order(100,104,143,157,159,221,238,265)
                     /site_type="active"
                     /note="putative effector binding pocket [active]"
                     /db_xref="CDD:176114"
     Site            order(101..102,106..107,109..110,113,117,119..125,186,
                     215..219,226..227,230)
                     /site_type="other"
                     /note="dimerization interface [polypeptide binding]"
                     /db_xref="CDD:176114"
ORIGIN      
        1 mdrviaaqvy lricelgsls aaaralgmsr pmvsryleqm eswagarlih rstrrltltp
       61 agekvllktr gltriadeia gerqradpsg tlrvacahft amqlispllp dflarypllr
      121 leldinnhpv sligeridva iritdnpeag aiarrlgvcr sllcaaprwm rqhgplttpd
      181 dlqrhnclly shfasqhwqf sdaqgreasv avngnlsagi ssllleaava gcgiamlpel
      241 eargaidsgt levvlpewtp kalsvygiyl srdyqpdglp lfldalqrrl geetghg