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MULTISPECIES: pyrroloquinoline quinone biosynthesis protein PqqB


LOCUS       WP_004199996             308 aa            linear   BCT 26-AUG-2024
            [Klebsiella].
ACCESSION   WP_004199996
VERSION     WP_004199996.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 308)
  AUTHORS   Koehn,E.M., Latham,J.A., Armand,T., Evans,R.L. 3rd, Tu,X.,
            Wilmot,C.M., Iavarone,A.T. and Klinman,J.P.
  TITLE     Discovery of Hydroxylase Activity for PqqB Provides a Missing Link
            in the Pyrroloquinoline Quinone Biosynthetic Pathway
  JOURNAL   J Am Chem Soc 141 (10), 4398-4405 (2019)
   PUBMED   30811189
REFERENCE   2  (residues 1 to 308)
  AUTHORS   Tu,X., Latham,J.A., Klema,V.J., Evans,R.L. 3rd, Li,C., Klinman,J.P.
            and Wilmot,C.M.
  TITLE     Crystal structures reveal metal-binding plasticity at the
            metallo-beta-lactamase active site of PqqB from Pseudomonas putida
  JOURNAL   J Biol Inorg Chem 22 (7), 1089-1097 (2017)
   PUBMED   28825148
REFERENCE   3  (residues 1 to 308)
  AUTHORS   Goosen,N., Horsman,H.P., Huinen,R.G. and van de Putte,P.
  TITLE     Acinetobacter calcoaceticus genes involved in biosynthesis of the
            coenzyme pyrrolo-quinoline-quinone: nucleotide sequence and
            expression in Escherichia coli K-12
  JOURNAL   J Bacteriol 171 (1), 447-455 (1989)
   PUBMED   2536663
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR02108.2
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..308
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..308
                     /gene="pqqB"
     Protein         1..308
                     /product="pyrroloquinoline quinone biosynthesis protein
                     PqqB"
                     /GO_process="GO:0018189 - pyrroloquinoline quinone
                     biosynthetic process [Evidence IEA]"
                     /calculated_mol_wt=33311
     Region          1..303
                     /region_name="PRK05184"
                     /note="pyrroloquinoline quinone biosynthesis protein PqqB;
                     Provisional"
                     /db_xref="CDD:235361"
     Site            order(88,90,92..93,176..177,199,220)
                     /site_type="active"
                     /note="putative active site [active]"
                     /db_xref="CDD:293832"
     Site            order(92,220)
                     /site_type="other"
                     /note="putative metal binding site [ion binding]"
                     /db_xref="CDD:293832"
ORIGIN      
        1 mfikvlgsaa gggfpqwncn cancqglrdg tiqaaprtqs siivsdngke wvlcnaspdi
       61 sqqiantpel nkagvlrgth iggiiltdsq idhttgllsl regcphqvwc tpevhedlst
      121 gfpvftmlrh wngglvhhpi apqqpftvda cpdlqftavp iasnappysp yrdrplpghn
      181 valfienrrn gqtlfyapgl gepdetllpw lqkadcllid gtvwqddelq aagvgrntgr
      241 dmghlalgde hgmmallasl pakrkilihi nntnpilneq spqrqaltqq gievswdgma
      301 itlqdtac