MULTISPECIES: MFS transporter [Klebsiella].

LOCUS       WP_004199920             402 aa            linear   BCT 31-DEC-2024
ACCESSION   WP_004199920
VERSION     WP_004199920.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 402)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 402)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
REFERENCE   3  (residues 1 to 402)
  AUTHORS   Yan,N.
  TITLE     Structural advances for the major facilitator superfamily (MFS)
            transporters
  JOURNAL   Trends Biochem Sci 38 (3), 151-159 (2013)
   PUBMED   23403214
REFERENCE   4  (residues 1 to 402)
  AUTHORS   Pao,S.S., Paulsen,I.T. and Saier,M.H. Jr.
  TITLE     Major facilitator superfamily
  JOURNAL   Microbiol Mol Biol Rev 62 (1), 1-34 (1998)
   PUBMED   9529885
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11457990
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..402
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..402
                     /product="MFS transporter"
                     /GO_component="GO:0005886 - plasma membrane [Evidence
                     IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=43489
     Region          15..346
                     /region_name="AraJ"
                     /note="Predicted arabinose efflux permease AraJ, MFS
                     family [Carbohydrate transport and metabolism]; COG2814"
                     /db_xref="CDD:442063"
ORIGIN      
        1 mplvtttfnq ktliriamvi afvqftnale ymmfspvftf maadfavpvt fsgyvsgmyt
       61 sgavlsgiia fywidrcnkk hflianmvll amatllttft tsfpllltlr ffaglvggtt
      121 mavgitilin htpadlrgkm latviasfsm vsivgmpavl flcthygwhv alwlictlcw
      181 lalplivsii pqdpvtfdts nalpldvdtl lfasgnalvq fspmliipvl aplmtqllga
      241 sqgllpwlff ggglagylst rmtgaltsrv salslatgst lvfilsllip vmgyphpalf
      301 itlflgaays rlvsssavti qfpdnkqrag fsslqtsmmy lmttaaffls afllpdhrma
      361 lqnmdtllav caitasgtpi ivivlqkkla krtfepdrft te