MULTISPECIES: nucleobase:cation symporter-2 family protein

LOCUS       WP_004199850             459 aa            linear   BCT 31-DEC-2024
            [Klebsiella].
ACCESSION   WP_004199850
VERSION     WP_004199850.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 459)
  AUTHORS   Chaliotis,A., Vlastaridis,P., Ntountoumi,C., Botou,M., Yalelis,V.,
            Lazou,P., Tatsaki,E., Mossialos,D., Frillingos,S. and
            Amoutzias,G.D.
  TITLE     NAT/NCS2-hound: a webserver for the detection and evolutionary
            classification of prokaryotic and eukaryotic nucleobase-cation
            symporters of the NAT/NCS2 family
  JOURNAL   Gigascience 7 (12), 5168872 (2018)
   PUBMED   30418564
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 459)
  AUTHORS   Frillingos,S.
  TITLE     Insights to the evolution of Nucleobase-Ascorbate Transporters
            (NAT/NCS2 family) from the Cys-scanning analysis of xanthine
            permease XanQ
  JOURNAL   Int J Biochem Mol Biol 3 (3), 250-272 (2012)
   PUBMED   23097742
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10799042
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..459
                     /product="nucleobase:cation symporter-2 family protein"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0015205 - nucleobase transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_process="GO:0015851 - nucleobase transport [Evidence
                     IEA]"
                     /calculated_mol_wt=47822
     Region          26..440
                     /region_name="pbuX"
                     /note="xanthine permease; TIGR03173"
                     /db_xref="CDD:274468"
ORIGIN      
        1 msdehhsgll ygleqrippl paffsalqhv laglvgiitp pliigatlgl gdwlpylism
       61 slmasgigtf lqsnrvwgig agmicmqgts faflgvtvag gmwvkaqggg pqdmmamlfg
      121 vnfvaalvpv ivsrfieplk kiftpiitgs vialigisli kvsvinwcgg ekaedfasms
      181 nialgagtlg vivllscakn rwlrlssvvv giavgciaag lsgqfhlhsl gdtlfrlptl
      241 fpfgfqfnsa iflpvalvsl vcileavgdl tanslisqqs vddrafrnrl kggiladgvs
      301 cmvaamlcaf pnttfaqnng viqmtgvasr yvgryigvil illglfppvg ellrqipapv
      361 lggatmvmfg cvvaagirii tqtplsrrdv livglafgag lgvesvpafl shfppmvgdl
      421 fgsaatsggl vaialnlilp qeqaatkslr sqddraesv