MULTISPECIES: molybdenum cofactor-independent xanthine hydroxylase

LOCUS       WP_004199847             324 aa            linear   BCT 13-MAY-2021
            subunit HpxE [Klebsiella].
ACCESSION   WP_004199847
VERSION     WP_004199847.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 324)
  AUTHORS   Pope,S.D., Chen,L.L. and Stewart,V.
  TITLE     Purine utilization by Klebsiella oxytoca M5al: genes for
            ring-oxidizing and -opening enzymes
  JOURNAL   J. Bacteriol. 191 (3), 1006-1017 (2009)
   PUBMED   19060149
REFERENCE   2  (residues 1 to 324)
  AUTHORS   de la Riva,L., Badia,J., Aguilar,J., Bender,R.A. and Baldoma,L.
  TITLE     The hpx genetic system for hypoxanthine assimilation as a nitrogen
            source in Klebsiella pneumoniae: gene organization and
            transcriptional regulation
  JOURNAL   J. Bacteriol. 190 (24), 7892-7903 (2008)
   PUBMED   18849434
REFERENCE   3  (residues 1 to 324)
  AUTHORS   Garzon,A., Li,J., Flores,A., Casadesus,J. and Stewart,V.
  TITLE     Molybdenum cofactor (chlorate-resistant) mutants of Klebsiella
            pneumoniae M5al can use hypoxanthine as the sole nitrogen source
  JOURNAL   J. Bacteriol. 174 (19), 6298-6302 (1992)
   PUBMED   1400180
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR006062
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..324
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..324
                     /gene="hpxE"
     Protein         1..324
                     /product="molybdenum cofactor-independent xanthine
                     hydroxylase subunit HpxE"
                     /calculated_mol_wt=34470
     Region          20..222
                     /region_name="PDR_like"
                     /note="Phthalate dioxygenase reductase (PDR) is an
                     FMN-dependent reductase that mediates electron transfer
                     from NADH to FMN to an iron sulfur cluster. PDR has an an
                     N-terminal ferrredoxin reductase (FNR)-like NAD(H) binding
                     domain and a C-terminal iron-sulfur...; cd06185"
                     /db_xref="CDD:99782"
     Site            order(51..52,54,68..70,76,78..79,119,221)
                     /site_type="other"
                     /note="FMN-binding pocket [chemical binding]"
                     /db_xref="CDD:99782"
     Site            order(51,53..54)
                     /site_type="active"
                     /note="flavin binding motif [active]"
                     /db_xref="CDD:99782"
     Site            order(76,79,82,89)
                     /site_type="other"
                     /note="phosphate binding motif [ion binding]"
                     /db_xref="CDD:99782"
     Site            order(111,115..118,120)
                     /site_type="other"
                     /note="beta-alpha-beta structure motif"
                     /db_xref="CDD:99782"
     Site            order(116..117,140..142,194..195)
                     /site_type="other"
                     /note="NAD binding pocket [chemical binding]"
                     /db_xref="CDD:99782"
     Region          237..323
                     /region_name="Fdx"
                     /note="Ferredoxin [Energy production and conversion];
                     COG0633"
                     /db_xref="CDD:440398"
ORIGIN      
        1 mrdilpvvvd glwrqgaknl avrlvsaegq plpawtpgsh idlhlpcgli rqysltgspa
       61 eqdryllcia resqsrggsr yihdtlrpgq plmisaprnh fplhegghvv llaagigitp
      121 llamaharaa sgasftlhyy vsraqeaafa teiarqlsgg icqihcsdeg qsprqrlaqd
      181 lgapdadtrv yfcgppgfma rvrdtaravg weeaqlhsea fqppaptaas aadgtftitl
      241 astgerwpvp gdktiaqvlq ehgvavplsc emgicgaclt pvregtvdhr dtvqseaekq
      301 aaeqhialcc srslsanlvi dlag