MULTISPECIES: mechanosensitive ion channel family protein

LOCUS       WP_004198878             538 aa            linear   BCT 31-DEC-2024
            [Klebsiella].
ACCESSION   WP_004198878
VERSION     WP_004198878.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 538)
  AUTHORS   Cox,C.D., Nakayama,Y., Nomura,T. and Martinac,B.
  TITLE     The evolutionary 'tinkering' of MscS-like channels: generation of
            structural and functional diversity
  JOURNAL   Pflugers Arch 467 (1), 3-13 (2015)
   PUBMED   24819593
REFERENCE   2  (residues 1 to 538)
  AUTHORS   Malcolm,H.R. and Maurer,J.A.
  TITLE     The mechanosensitive channel of small conductance (MscS)
            superfamily: not just mechanosensitive channels anymore
  JOURNAL   Chembiochem 13 (14), 2037-2043 (2012)
   PUBMED   22915507
REFERENCE   3  (residues 1 to 538)
  AUTHORS   Haswell,E.S., Phillips,R. and Rees,D.C.
  TITLE     Mechanosensitive channels: what can they do and how do they do it?
  JOURNAL   Structure 19 (10), 1356-1369 (2011)
   PUBMED   22000509
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11461657
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..538
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..538
                     /product="mechanosensitive ion channel family protein"
                     /GO_function="GO:0008381 - mechanosensitive monoatomic ion
                     channel activity [Evidence IEA]"
                     /calculated_mol_wt=59983
     Region          251..508
                     /region_name="MscK"
                     /note="Small-conductance mechanosensitive channel MscK
                     [Cell wall/membrane/envelope biogenesis]; COG3264"
                     /db_xref="CDD:442495"
ORIGIN      
        1 mnrmsivilw alallvlqpa laaeprqqpt areqartvti fhqpvvmlqa tfgqttpeer
       61 vlrtrsalra fteddirqpl rvvpvirygq pgrlllmngk pvlllsqadl degddltldq
      121 aaqrvlarme aqrtslqeqf nnrylfisag kalagallla lfyygafraw rrvrrffllr
      181 ilekrsaipq hwrrylgnie vrlyavlvil lgmlacylwl swafslfpwt rvwseslgdw
      241 slgvirhlsl sivaslpglm ivvliflltw liirlvkvvl dqvaagriqi pgihpetvsa
      301 trrlisvviw lfalsaaypf lpganslafk gislffglml tlgstgvmth amsglvliys
      361 ralrkgdwir ladnegqvse igvlatkilt renyivtvpn avvvsgkiin lsaesadggv
      421 nlttsvtigy dtpwrqvhal lelaarrtpg idqqiapvvr klglldwyts yelqvrllpt
      481 tklpdgrnal hssiidvfne fgvqimspnf vmqpkaavvv pqeawyaapa vapqepek