sensor histidine kinase [Klebsiella pneumoniae].

LOCUS       WP_004197104             559 aa            linear   BCT 23-MAR-2023
ACCESSION   WP_004197104
VERSION     WP_004197104.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group;
            Klebsiella; Klebsiella pneumoniae complex.
REFERENCE   1  (residues 1 to 559)
  AUTHORS   Dutta,R. and Inouye,M.
  TITLE     GHKL, an emergent ATPase/kinase superfamily
  JOURNAL   Trends Biochem Sci 25 (1), 24-28 (2000)
   PUBMED   10637609
REFERENCE   2  (residues 1 to 559)
  AUTHORS   Stock,J.
  TITLE     Signal transduction: Gyrating protein kinases
  JOURNAL   Curr Biol 9 (10), R364-R367 (1999)
   PUBMED   10339418
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11461692
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..559
                     /organism="Klebsiella pneumoniae"
                     /db_xref="taxon:573"
     Protein         1..559
                     /product="sensor histidine kinase"
                     /EC_number="2.7.13.3"
                     /GO_function="GO:0000155 - phosphorelay sensor kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0004673 - protein histidine kinase
                     activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /calculated_mol_wt=61641
     Region          23..188
                     /region_name="5TM-5TMR_LYT"
                     /note="5TMR of 5TMR-LYT; pfam07694"
                     /db_xref="CDD:429599"
     Region          222..335
                     /region_name="GAF_2"
                     /note="GAF domain; pfam13185"
                     /db_xref="CDD:433019"
     Region          <291..545
                     /region_name="LytS"
                     /note="Sensor histidine kinase, LytS/YehU family [Signal
                     transduction mechanisms]; COG3275"
                     /db_xref="CDD:442506"
ORIGIN      
        1 mmlavydraa lmliclffli rlrlfrellh ksahtpkell avtaifslfa lfstwsgvpv
       61 egslvnvrii avmsggilfg pwvgaivgai agvhrylidi dgvtavpcfi tsivagllsg
      121 linrkvareq rwkigilagm mcetltmilv vvwapslslg vdivskigip milgsvcigf
      181 ivllvqsveg ekeasaarqa klaldiankt lplfrhvnsd slrqvceiir rditadavai
      241 tntehvlayv gvgeanyqrh ddmispttrq airygkiiik nndeahrtpe ihslmviplw
      301 ekgvvtgtlk iyychahrit stlqemaigl sqiistqlev sraeqlrema nkaelralqs
      361 kinphflfna lnaisssirl npdtarqlif nlsrylryni elkddeqidi krelyqikdy
      421 iaieqarfgd kltviydidd dvscvipsll iqplvenaiv hgiqpckgkg vvtiginecg
      481 nrvrisvrdt gngidpavva rveadempgn kigllnvhhr vkllygeglh irnltpgtei
      541 afyvpnnstp qalteslls