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beta-ketoacyl-ACP synthase II [Klebsiella pneumoniae].


LOCUS       WP_004195946             401 aa            linear   BCT 23-JUL-2023
ACCESSION   WP_004195946
VERSION     WP_004195946.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group;
            Klebsiella; Klebsiella pneumoniae complex.
REFERENCE   1  (residues 1 to 401)
  AUTHORS   von Wettstein-Knowles,P., Olsen,J.G., McGuire,K.A. and Henriksen,A.
  TITLE     Fatty acid synthesis. Role of active site histidines and lysine in
            Cys-His-His-type beta-ketoacyl-acyl carrier protein synthases
  JOURNAL   FEBS J. 273 (4), 695-710 (2006)
   PUBMED   16441657
REFERENCE   2  (residues 1 to 401)
  AUTHORS   Moche,M., Dehesh,K., Edwards,P. and Lindqvist,Y.
  TITLE     The crystal structure of beta-ketoacyl-acyl carrier protein
            synthase II from Synechocystis sp. at 1.54 A resolution and its
            relationship to other condensing enzymes
  JOURNAL   J. Mol. Biol. 305 (3), 491-503 (2001)
   PUBMED   11152607
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR03150.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..401
                     /organism="Klebsiella pneumoniae"
                     /db_xref="taxon:573"
     gene            1..401
                     /gene="fabF"
     Protein         1..401
                     /product="beta-ketoacyl-ACP synthase II"
                     /EC_number="2.3.1.179"
                     /GO_function="GO:0004315 -
                     3-oxoacyl-[acyl-carrier-protein] synthase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006633 - fatty acid biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=41444
     Region          1..401
                     /region_name="PRK07314"
                     /note="beta-ketoacyl-ACP synthase II"
                     /db_xref="CDD:235987"
     Site            order(96,103..104,108,110..111,123,129,133,137,143,145,
                     147..149,161,164..165,168,189..190,193..194,252..256,270,
                     390,392)
                     /site_type="other"
                     /note="dimer interface [polypeptide binding]"
                     /db_xref="CDD:238430"
     Site            order(152,292,329)
                     /site_type="active"
                     /db_xref="CDD:238430"
ORIGIN      
        1 mlspvgntve stwkallagq sgislidhfd tsayatkfag lvkdfncddi isrkeqrkmd
       61 afiqygivag vqamqdsgle vteenatrig aaigsgiggl glieenhssl vnggprkisp
      121 ffvpstivnm vaghltimfg lrgpsisiat actsgvhnig qaariiaygd adamvaggae
      181 kastplgvgg fgaaralstr ndnpqaasrp wdkdrdgfvl gdgagmvvle eyehakkrga
      241 kiyaeivgfg mssdayhmts ppedgagaal amvnairdag iepgqigyvn ahgtstpagd
      301 kaeaqavksv fgdaasrvlv sstksmtghl lgaagavesi ysilalrdqa vpptinldnp
      361 degcdldfvp hearqvsgme ytlcnsfgfg gtngslifkk v