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exodeoxyribonuclease III [Klebsiella pneumoniae].


LOCUS       WP_004190821             301 aa            linear   BCT 15-MAY-2023
ACCESSION   WP_004190821
VERSION     WP_004190821.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group;
            Klebsiella; Klebsiella pneumoniae complex.
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF008733.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK11756
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..301
                     /organism="Klebsiella pneumoniae"
                     /db_xref="taxon:573"
     gene            1..301
                     /gene="xthA"
     Protein         1..301
                     /product="exodeoxyribonuclease III"
                     /EC_number="3.1.11.2"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0004519 - endonuclease activity [Evidence
                     IEA]"
                     /GO_function="GO:0008311 - double-stranded DNA 3'-5'
                     exodeoxyribonuclease activity [Evidence IEA]"
                     /GO_process="GO:0006281 - DNA repair [Evidence IEA]"
                     /calculated_mol_wt=34273
     Region          34..300
                     /region_name="PRK11756"
                     /note="exonuclease III; Provisional"
                     /db_xref="CDD:236970"
     Site            order(40,67,142,145,184,186,292)
                     /site_type="other"
                     /note="putative phosphate binding site [ion binding]"
                     /db_xref="CDD:197320"
     Site            order(40,67,142,184,186,262,291..292)
                     /site_type="active"
                     /note="putative catalytic site [active]"
                     /db_xref="CDD:197320"
     Site            order(42..43,45..47,67,93..94,142,145,147,154,184,186,245,
                     248..249,259,261..262,288..289,292)
                     /site_type="active"
                     /db_xref="CDD:197320"
     Site            order(42,67,291..292)
                     /site_type="metal-binding"
                     /note="metal binding site A [ion binding]"
                     /db_xref="CDD:197320"
     Site            order(42..43,45..47,93..94,142,145,147,154,248..249,
                     288..289)
                     /site_type="DNA binding"
                     /note="DNA binding site [nucleotide binding]"
                     /db_xref="CDD:197320"
     Site            order(142,145,184,186,245,259,261,292)
                     /site_type="other"
                     /note="putative AP binding site [nucleotide binding]"
                     /db_xref="CDD:197320"
     Site            order(142,184,186,292)
                     /site_type="other"
                     /note="putative metal binding site B [ion binding]"
                     /db_xref="CDD:197320"
ORIGIN      
        1 mrsdwqndas ggsqpgefll pslhyspctv aatmkfvsfn inglrarphq laaivekhqp
       61 dviglqetkv hddmfpleev arlgynvfyh gqkghygval ltketpiavr rgfpddgeea
      121 qrriimaeip spfgnvtvin gyfpqgesrd hetkfpakaa fyqnlqnyle telnkenpvl
      181 imgdmnispt dldigigeen rkrwlrtgkc sflpeerewm drllgwglvd twrqanpdnh
      241 ehfswfdyrs kgfddnrglr idlllasqpl aqrcvetgid yeirgmekps dhapvwatfr
      301 p