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MULTISPECIES: LysR family transcriptional regulator [Klebsiella].


LOCUS       WP_004189584             296 aa            linear   BCT 31-DEC-2024
ACCESSION   WP_004189584
VERSION     WP_004189584.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 296)
  AUTHORS   Maddocks,S.E. and Oyston,P.C.F.
  TITLE     Structure and function of the LysR-type transcriptional regulator
            (LTTR) family proteins
  JOURNAL   Microbiology (Reading) 154 (Pt 12), 3609-3623 (2008)
   PUBMED   19047729
REFERENCE   2  (residues 1 to 296)
  AUTHORS   Schell,M.A.
  TITLE     Molecular biology of the LysR family of transcriptional regulators
  JOURNAL   Annu Rev Microbiol 47, 597-626 (1993)
   PUBMED   8257110
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10444078
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..296
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..296
                     /product="LysR family transcriptional regulator"
                     /GO_component="GO:0005829 - cytosol [Evidence IEA]"
                     /GO_function="GO:0003677 - DNA binding [Evidence IEA]"
                     /GO_function="GO:0003700 - DNA-binding transcription
                     factor activity [Evidence IEA]"
                     /calculated_mol_wt=32080
     Region          6..64
                     /region_name="HTH_1"
                     /note="Bacterial regulatory helix-turn-helix protein, lysR
                     family; pfam00126"
                     /db_xref="CDD:459683"
     Region          94..290
                     /region_name="PBP2_LTTR_like_4"
                     /note="TThe C-terminal substrate binding domain of an
                     uncharacterized LysR-type transcriptional regulator,
                     contains the type 2 periplasmic binding fold; cd08440"
                     /db_xref="CDD:176131"
     Site            order(109..110,112..113,116,120,122..128,220..225,
                     231..232,234..235)
                     /site_type="other"
                     /note="putative dimerization interface [polypeptide
                     binding]"
                     /db_xref="CDD:176131"
ORIGIN      
        1 mrmsvkqlra flavahtlnf ahaserlnls qpalsltikg leealggall qrstrkvtlt
       61 qegelflpma rqlladwdnv eeamrqsftl qrgkisvaam psfaanvlpe alkafrdrya
      121 gvnvtvhdvi neqviemvre grvemgiafe pspnhnllft plavdrfvai vpqqsplakk
      181 kqltwqellt ldfitlqrps avrlmleeal arsgrqldva leshqlvtvg rmvasglggs
      241 avpalcktqm aslgavcipl sdppiekcvg aihaghlpls kaaqalldtl kgflpt