MULTISPECIES: HTH-type transcriptional regulator Cbl [Klebsiella].

LOCUS       WP_004180456             316 aa            linear   BCT 20-NOV-2023
ACCESSION   WP_004180456
VERSION     WP_004180456.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 316)
  AUTHORS   Stec,E., Witkowska-Zimny,M., Hryniewicz,M.M., Neumann,P.,
            Wilkinson,A.J., Brzozowski,A.M., Verma,C.S., Zaim,J., Wysocki,S.
            and Bujacz,G.D.
  TITLE     Structural basis of the sulphate starvation response in E. coli:
            crystal structure and mutational analysis of the cofactor-binding
            domain of the Cbl transcriptional regulator
  JOURNAL   J. Mol. Biol. 364 (3), 309-322 (2006)
   PUBMED   17010379
REFERENCE   2  (residues 1 to 316)
  AUTHORS   Lochowska,A., Iwanicka-Nowicka,R., Zaim,J., Witkowska-Zimny,M.,
            Bolewska,K. and Hryniewicz,M.M.
  TITLE     Identification of activating region (AR) of Escherichia coli
            LysR-type transcription factor CysB and CysB contact site on RNA
            polymerase alpha subunit at the cysP promoter
  JOURNAL   Mol. Microbiol. 53 (3), 791-806 (2004)
   PUBMED   15255893
REFERENCE   3  (residues 1 to 316)
  AUTHORS   Jovanovic,M., Lilic,M., Savic,D.J. and Jovanovic,G.
  TITLE     The LysR-type transcriptional regulator CysB controls the
            repression of hslJ transcription in Escherichia coli
  JOURNAL   Microbiology (Reading, Engl.) 149 (Pt 12), 3449-3459 (2003)
   PUBMED   14663078
REFERENCE   4  (residues 1 to 316)
  AUTHORS   Bykowski,T., van der Ploeg,J.R., Iwanicka-Nowicka,R. and
            Hryniewicz,M.M.
  TITLE     The switch from inorganic to organic sulphur assimilation in
            Escherichia coli: adenosine 5'-phosphosulphate (APS) as a
            signalling molecule for sulphate excess
  JOURNAL   Mol. Microbiol. 43 (5), 1347-1358 (2002)
   PUBMED   11918818
REFERENCE   5  (residues 1 to 316)
  AUTHORS   Lochowska,A., Iwanicka-Nowicka,R., Plochocka,D. and Hryniewicz,M.M.
  TITLE     Functional dissection of the LysR-type CysB transcriptional
            regulator. Regions important for DNA binding, inducer response,
            oligomerization, and positive control
  JOURNAL   J. Biol. Chem. 276 (3), 2098-2107 (2001)
   PUBMED   11038360
REFERENCE   6  (residues 1 to 316)
  AUTHORS   Tyrrell,R., Verschueren,K.H., Dodson,E.J., Murshudov,G.N., Addy,C.
            and Wilkinson,A.J.
  TITLE     The structure of the cofactor-binding fragment of the LysR family
            member, CysB: a familiar fold with a surprising subunit arrangement
  JOURNAL   Structure 5 (8), 1017-1032 (1997)
   PUBMED   9309218
REFERENCE   7  (residues 1 to 316)
  AUTHORS   Iwanicka-Nowicka,R. and Hryniewicz,M.M.
  TITLE     A new gene, cbl, encoding a member of the LysR family of
            transcriptional regulators belongs to Escherichia coli cys regulon
  JOURNAL   Gene 166 (1), 11-17 (1995)
   PUBMED   8529872
REFERENCE   8  (residues 1 to 316)
  AUTHORS   Miller,B.E. and Kredich,N.M.
  TITLE     Purification of the cysB protein from Salmonella typhimurium
  JOURNAL   J. Biol. Chem. 262 (13), 6006-6009 (1987)
   PUBMED   3032953
REFERENCE   9  (residues 1 to 316)
  AUTHORS   Bielinska,A. and Hulanicka,D.
  TITLE     Regulation of the cysB gene expression in Escherichia coli
  JOURNAL   Acta Biochim. Pol. 33 (2), 133-137 (1986)
   PUBMED   3094306
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF009324.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK12679
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..316
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..316
                     /gene="cbl"
     Protein         1..316
                     /product="HTH-type transcriptional regulator Cbl"
                     /GO_function="GO:0003700 - DNA-binding transcription
                     factor activity [Evidence IEA]"
                     /GO_process="GO:0006355 - regulation of transcription,
                     DNA-templated [Evidence IEA]"
                     /calculated_mol_wt=35544
     Region          1..316
                     /region_name="cbl"
                     /note="HTH-type transcriptional regulator Cbl; PRK12679"
                     /db_xref="CDD:183676"
ORIGIN      
        1 mnfqqlkiir eaarqdynlt evanmlytsq sgvsrhirel eeelgieifi rrgkrllgmt
       61 epgkallsia erilneasnv rrladlftnd asgvltiatt htqaryslpp vikafrelfs
      121 dvrvelvqgt pqeieallhn ggadigiase rlsndptlaa fpwfrwhhsl lvpkdhpltq
      181 vspltleaia rwplityrqg itgrsridea fnrkglmpdi vlsaqdsdvi ktyvelglgv
      241 glvaeqsgda readtftrld trhlfdantv wlglkrgqlq rnyvwrfiel cnaglsldei
      301 krqamepeea aidyqi