MULTISPECIES: MBL fold metallo-hydrolase [Klebsiella].

LOCUS       WP_004180178             278 aa            linear   BCT 01-JAN-2025
ACCESSION   WP_004180178
VERSION     WP_004180178.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 278)
  AUTHORS   Bebrone,C.
  TITLE     Metallo-beta-lactamases (classification, activity, genetic
            organization, structure, zinc coordination) and their superfamily
  JOURNAL   Biochem Pharmacol 74 (12), 1686-1701 (2007)
   PUBMED   17597585
REFERENCE   2  (residues 1 to 278)
  AUTHORS   Callebaut,I., Moshous,D., Mornon,J.P. and de Villartay,J.P.
  TITLE     Metallo-beta-lactamase fold within nucleic acids processing
            enzymes: the beta-CASP family
  JOURNAL   Nucleic Acids Res 30 (16), 3592-3601 (2002)
   PUBMED   12177301
REFERENCE   3  (residues 1 to 278)
  AUTHORS   Daiyasu,H., Osaka,K., Ishino,Y. and Toh,H.
  TITLE     Expansion of the zinc metallo-hydrolase family of the
            beta-lactamase fold
  JOURNAL   FEBS Lett 503 (1), 1-6 (2001)
   PUBMED   11513844
REFERENCE   4  (residues 1 to 278)
  AUTHORS   Aravind,L.
  TITLE     An evolutionary classification of the metallo-beta-lactamase fold
            proteins
  JOURNAL   In Silico Biol 1 (2), 69-91 (1999)
   PUBMED   11471246
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10869928
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..278
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..278
                     /product="MBL fold metallo-hydrolase"
                     /EC_number="3.-.-.-"
                     /GO_function="GO:0016787 - hydrolase activity [Evidence
                     IEA]"
                     /GO_function="GO:0046872 - metal ion binding [Evidence
                     IEA]"
                     /calculated_mol_wt=29199
     Region          12..257
                     /region_name="OPHC2-like_MBL-fold"
                     /note="Pseudomonas pseudoalcaligenes organophosphorus
                     hydrolase C2, and related proteins; MBL-fold metallo
                     hydrolase domain; cd07720"
                     /db_xref="CDD:293806"
     Site            order(24,105,107,109..110,138,189,210,213,226,228,257)
                     /site_type="active"
                     /db_xref="CDD:293806"
ORIGIN      
        1 mspapfytlt agdltvtavs dglmsaplsl lsgisreeae hlqrhsglas petiaigayl
       61 irgrgntvlv dtgtggangv ggelianlar lgvgpeeida illthahpdh iggllsaagt
      121 paypnatvfl ptresaywla tstfdnasdr grrnvllvrr vlancaaqis gvddeeviag
      181 irpcplpght pghtgyrlea gdtslliwgd ivhfpsiqsa rpeasvafdv dpeqarrtre
      241 illrqaaser wliagmhlgl pgfarventa sgyclrsv