MULTISPECIES: pyridoxal-phosphate-dependent aminotransferase family

LOCUS       WP_004179945             413 aa            linear   BCT 24-DEC-2024
            protein [Klebsiella].
ACCESSION   WP_004179945
VERSION     WP_004179945.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 413)
  AUTHORS   Koper,K., Han,S.W., Kothadia,R., Salamon,H., Yoshikuni,Y. and
            Maeda,H.A.
  TITLE     Multisubstrate specificity shaped the complex evolution of the
            aminotransferase family across the tree of life
  JOURNAL   Proc Natl Acad Sci U S A 121 (26), e2405524121 (2024)
   PUBMED   38885378
REFERENCE   2  (residues 1 to 413)
  AUTHORS   Koper,K., Han,S.W., Pastor,D.C., Yoshikuni,Y. and Maeda,H.A.
  TITLE     Evolutionary origin and functional diversification of
            aminotransferases
  JOURNAL   J Biol Chem 298 (8), 102122 (2022)
   PUBMED   35697072
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11414660
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..413
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..413
                     /product="pyridoxal-phosphate-dependent aminotransferase
                     family protein"
                     /EC_number="2.6.1.-"
                     /GO_function="GO:0030170 - pyridoxal phosphate binding
                     [Evidence IEA]"
                     /calculated_mol_wt=45872
     Region          14..408
                     /region_name="PucG"
                     /note="Archaeal aspartate aminotransferase or a related
                     aminotransferase, includes purine catabolism protein PucG
                     [Amino acid transport and metabolism, Nucleotide transport
                     and metabolism]; COG0075"
                     /db_xref="CDD:439845"
ORIGIN      
        1 mditqfsqin ppqrllmgpg pinadprvlr amssqlvgqy dpamthymne vmalyrgvfr
       61 tenrwtmlvd gtsragieai llsairpgdk vlvpvfgrfg hllceiarrc raevhtievp
      121 wgevftpdqv edaikrvrpr llltvqgdts ttmlqplael geicrrhdvl fytdataslg
      181 gnpletdawq ldavsagmqk clggpsgtsp itlsprmeev irrrrcieqg irtdahhdgv
      241 demiysnyfd lgmvmdywgp erlnhhteat salfaareca rlilqegldn giarhklhgd
      301 allkgiqamg letfgdlrhk mnnvlgvvip ngvngdqvrk lmledfgiei gtsfgplhgk
      361 vwrigtmgyn arkdcvmqtl saleavlnyl rftttqgaam qaawdhyrte atl