MULTISPECIES: EAL domain-containing protein [Klebsiella].

LOCUS       WP_004177824             534 aa            linear   BCT 19-FEB-2025
ACCESSION   WP_004177824
VERSION     WP_004177824.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 534)
  AUTHORS   Simm,R., Morr,M., Kader,A., Nimtz,M. and Romling,U.
  TITLE     GGDEF and EAL domains inversely regulate cyclic di-GMP levels and
            transition from sessility to motility
  JOURNAL   Mol Microbiol 53 (4), 1123-1134 (2004)
   PUBMED   15306016
REFERENCE   2  (residues 1 to 534)
  AUTHORS   D'Argenio,D.A. and Miller,S.I.
  TITLE     Cyclic di-GMP as a bacterial second messenger
  JOURNAL   Microbiology (Reading) 150 (Pt 8), 2497-2502 (2004)
   PUBMED   15289546
REFERENCE   3  (residues 1 to 534)
  AUTHORS   Galperin,M.Y., Nikolskaya,A.N. and Koonin,E.V.
  TITLE     Novel domains of the prokaryotic two-component signal transduction
            systems
  JOURNAL   FEMS Microbiol Lett 203 (1), 11-21 (2001)
   PUBMED   11557134
  REMARK    Erratum:[FEMS Microbiol Lett 2001 Oct 16;204(1):213-4]
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11471819
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..534
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..534
                     /product="EAL domain-containing protein"
                     /EC_number="3.1.4.52"
                     /GO_component="GO:0005886 - plasma membrane [Evidence
                     IEA]"
                     /GO_function="GO:0071111 - cyclic-guanylate-specific
                     phosphodiesterase activity [Evidence IEA]"
                     /GO_process="GO:0007165 - signal transduction [Evidence
                     IEA]"
                     /calculated_mol_wt=60229
     Region          7..527
                     /region_name="YjcC"
                     /note="Redox-sensing c-di-GMP phosphodiesterase, contains
                     CSS-motif and EAL domains [Signal transduction
                     mechanisms]; COG4943"
                     /db_xref="CDD:443970"
ORIGIN      
        1 mgdsaphkal rligtglvil lpvvlalwfa qlrakaetid qlhsfsqlal qktemvirea
       61 dqarakasqy rgelcsadhq ryllhivrgl lyvedliyan gqrficstsv hqqtgwrmpa
      121 anytkkpdva iyyyrdtpfy pgfamnymqk gpyvvvvnpf syssviasdr dlaygvfdtk
      181 tnlffsvsnn vepaelhali regdtffnqn grvytiarsa irpiavimst srasyyhnfc
      241 dqasltlplg iicsillvlv wsrtrrqyhs prnmlqrals crqlrlhyqp iidiknnrcv
      301 gaeallrwpg fdgpvmnpae fiplaenegm iaqvtdyvvd elfyemgefl ashpqlyiai
      361 nlsasdfhsa rlisqiseka hsyavcigqi kievtergfi dvpkttpviq afreagyeia
      421 iddfgtgysn lhnlhalnvd ilkidktfvd tlttnntshl iaehiiemar glrlktiaeg
      481 vetpeqvswl ykrgvqycqg wlfakampar efmqwlanap apanvpqppr haei