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LOCUS WP_004177299 221 aa linear BCT 24-DEC-2024 ACCESSION WP_004177299 VERSION WP_004177299.1 KEYWORDS RefSeq. SOURCE Klebsiella ORGANISM Klebsiella Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group. REFERENCE 1 (residues 1 to 221) AUTHORS Leader,D.P. and Milner-White,E.J. TITLE The conserved crown bridge loop at the catalytic centre of enzymes of the haloacid dehalogenase superfamily JOURNAL Curr Res Struct Biol 6, 100105 (2023) PUBMED 37786806 REMARK Publication Status: Online-Only REFERENCE 2 (residues 1 to 221) AUTHORS Yang,L., Lu,Y., Tian,W., Feng,Y., Bai,J. and Zhang,H. TITLE Insights into the functional divergence of the haloacid dehalogenase superfamily from phosphomonoesterase to inorganic pyrophosphatase JOURNAL Arch Biochem Biophys 705, 108896 (2021) PUBMED 33940035 REFERENCE 3 (residues 1 to 221) AUTHORS Burroughs,A.M., Allen,K.N., Dunaway-Mariano,D. and Aravind,L. TITLE Evolutionary genomics of the HAD superfamily: understanding the structural adaptations and catalytic diversity in a superfamily of phosphoesterases and allied enzymes JOURNAL J Mol Biol 361 (5), 1003-1034 (2006) PUBMED 16889794 REFERENCE 4 (residues 1 to 221) AUTHORS Allen,K.N. and Dunaway-Mariano,D. TITLE Phosphoryl group transfer: evolution of a catalytic scaffold JOURNAL Trends Biochem Sci 29 (9), 495-503 (2004) PUBMED 15337123 COMMENT REFSEQ: This record represents a single, non-redundant, protein sequence which may be annotated on many different RefSeq genomes from the same, or different, species. ##Evidence-For-Name-Assignment-START## Evidence Category :: Conserved Domain (CDD) Evidence Accession :: Domain architecture ID 10001729 Evidence Source :: NCBI SPARCLE ##Evidence-For-Name-Assignment-END## COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..221 /organism="Klebsiella" /db_xref="taxon:570" Protein 1..221 /product="HAD family hydrolase" /EC_number="3.-.-.-" /GO_function="GO:0016787 - hydrolase activity [Evidence IEA]" /calculated_mol_wt=24192 Region 1..219 /region_name="SerB" /note="Phosphoserine phosphatase [Amino acid transport and metabolism]; COG0560" /db_xref="CDD:440326" ORIGIN 1 mgntltifdl dntliqgdss tvwsqfmvre glatqkgyla rearlmadyd rgemniadyv 61 aliqaplagi pksdvdalva rcvreailpr vypqawelir rlraegeqml iisasvsllv 121 qavaaaleid qalgidvamv dggysgeitg ipsyqqgkva rlaqwreahp qydgevtfyt 181 dsindlplcl hadrvrlvnp cpqlqaagag ygwpvlswrl e