NupC/NupG family nucleoside CNT transporter [Klebsiella

LOCUS       WP_004176604             405 aa            linear   BCT 01-JAN-2025
            pneumoniae].
ACCESSION   WP_004176604
VERSION     WP_004176604.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group;
            Klebsiella; Klebsiella pneumoniae complex.
REFERENCE   1  (residues 1 to 405)
  AUTHORS   Hirschi,M., Johnson,Z.L. and Lee,S.Y.
  TITLE     Visualizing multistep elevator-like transitions of a nucleoside
            transporter
  JOURNAL   Nature 545 (7652), 66-70 (2017)
   PUBMED   28424521
REFERENCE   2  (residues 1 to 405)
  AUTHORS   Johnson,Z.L., Lee,J.H., Lee,K., Lee,M., Kwon,D.Y., Hong,J. and
            Lee,S.Y.
  TITLE     Structural basis of nucleoside and nucleoside drug selectivity by
            concentrative nucleoside transporters
  JOURNAL   Elife 3, e03604 (2014)
   PUBMED   25082345
  REMARK    Publication Status: Online-Only
REFERENCE   3  (residues 1 to 405)
  AUTHORS   Munch-Petersen,A., Mygind,B., Nicolaisen,A. and Pihl,N.J.
  TITLE     Nucleoside transport in cells and membrane vesicles from
            Escherichia coli K12
  JOURNAL   J Biol Chem 254 (10), 3730-3737 (1979)
   PUBMED   374403
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11449426
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..405
                     /organism="Klebsiella pneumoniae"
                     /db_xref="taxon:573"
     Protein         1..405
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /GO_component="GO:0005886 - plasma membrane [Evidence
                     IEA]"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0005337 - nucleoside transmembrane
                     transporter activity [Evidence IEA]"
                     /GO_function="GO:0015293 - symporter activity [Evidence
                     IEA]"
                     /GO_process="GO:1901642 - nucleoside transmembrane
                     transport [Evidence IEA]"
                     /calculated_mol_wt=43793
     Region          32..405
                     /region_name="NupC"
                     /note="Nucleoside permease NupC [Nucleotide transport and
                     metabolism]; COG1972"
                     /db_xref="CDD:441575"
ORIGIN      
        1 maalltcekn nmtaffhfll alavilalaw lvsydrqkir iryilqliii eialaffflh
       61 aesglwlvkn isgffasllg faaegtnfvf ggmsekglaf iflgvlcpiv fisaligilq
      121 hwrilpifir vigtllskvn gmgklesfna vsslilgqse nfiaykgvlg dlssrrlftm
      181 aatamstvsl sivgaymtml dakyvvaali lnmfstfivl svinptrpgs eqeikleklh
      241 esqsffemlg eyilagfkva miilamligf ialisainal fatlfglsfq qilgyvfypl
      301 awligiplsd alnagsimat klvanefvam ielqkiaasm tprglgilsv flvsfanfas
      361 igiiagaikg lnepqgnivs rfglrlvysa tlvsllsasf aglvl