MULTISPECIES: MFS transporter [Enterobacterales].

LOCUS       WP_004176181             456 aa            linear   BCT 31-DEC-2024
ACCESSION   WP_004176181
VERSION     WP_004176181.1
KEYWORDS    RefSeq.
SOURCE      Enterobacterales
  ORGANISM  Enterobacterales
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria.
REFERENCE   1  (residues 1 to 456)
  AUTHORS   Quistgaard,E.M., Low,C., Guettou,F. and Nordlund,P.
  TITLE     Understanding transport by the major facilitator superfamily (MFS):
            structures pave the way
  JOURNAL   Nat Rev Mol Cell Biol 17 (2), 123-132 (2016)
   PUBMED   26758938
REFERENCE   2  (residues 1 to 456)
  AUTHORS   Yan,N.
  TITLE     Structural Biology of the Major Facilitator Superfamily
            Transporters
  JOURNAL   Annu Rev Biophys 44, 257-283 (2015)
   PUBMED   26098515
REFERENCE   3  (residues 1 to 456)
  AUTHORS   Pao,S.S., Paulsen,I.T. and Saier,M.H. Jr.
  TITLE     Major facilitator superfamily
  JOURNAL   Microbiol Mol Biol Rev 62 (1), 1-34 (1998)
   PUBMED   9529885
REFERENCE   4  (residues 1 to 456)
  AUTHORS   Marger,M.D. and Saier,M.H. Jr.
  TITLE     A major superfamily of transmembrane facilitators that catalyse
            uniport, symport and antiport
  JOURNAL   Trends Biochem Sci 18 (1), 13-20 (1993)
   PUBMED   8438231
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 11455192
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..456
                     /organism="Enterobacterales"
                     /db_xref="taxon:91347"
     Protein         1..456
                     /product="MFS transporter"
                     /GO_component="GO:0016020 - membrane [Evidence IEA]"
                     /GO_function="GO:0022857 - transmembrane transporter
                     activity [Evidence IEA]"
                     /GO_process="GO:0055085 - transmembrane transport
                     [Evidence IEA]"
                     /calculated_mol_wt=49958
     Region          27..453
                     /region_name="UhpC"
                     /note="Sugar phosphate permease [Carbohydrate transport
                     and metabolism]; COG2271"
                     /db_xref="CDD:441872"
ORIGIN      
        1 mlsrrrgvnt tmttinhtpa geqrgkkrli hrfswvsllv cwliwvlnay dremilrlgp
       61 viskefslsp eqwgnivali mvalavldip gsiwsdrygs gwkrarfqvp lvlgytalsf
      121 isgikaishg ltafvllrvg vnlgagwgep vgvsntaeww pkekrgfalg vhhtgypiga
      181 llsgvvaslv latfgegswr ycfllallva iplmifwaky stadrintly qhidsqgltr
      241 patqesshva kgegmktflr tlrnrnislt agntlltqiv ymginvvlpp ylyhvsglsl
      301 aasaglsiif tltgtlgqvi wpwlsdsfgr krtlivcglw msigialfyf atnmprliai
      361 qlffglvana vwpiyyamas dsaeeratst angiittamf igggispllm gwliqfgggw
      421 enpagyiyaf ftmagcallg mllqlmttdk tprkah