MULTISPECIES: tautomerase family protein [Klebsiella].

LOCUS       WP_004175282             129 aa            linear   BCT 07-NOV-2024
ACCESSION   WP_004175282
VERSION     WP_004175282.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 129)
  AUTHORS   Davidson,R., Baas,B.J., Akiva,E., Holliday,G.L., Polacco,B.J.,
            LeVieux,J.A., Pullara,C.R., Zhang,Y.J., Whitman,C.P. and
            Babbitt,P.C.
  TITLE     A global view of structure-function relationships in the
            tautomerase superfamily
  JOURNAL   J Biol Chem 293 (7), 2342-2357 (2018)
   PUBMED   29184004
REFERENCE   2  (residues 1 to 129)
  AUTHORS   Poelarends,G.J., Veetil,V.P. and Whitman,C.P.
  TITLE     The chemical versatility of the beta-alpha-beta fold: catalytic
            promiscuity and divergent evolution in the tautomerase superfamily
  JOURNAL   Cell Mol Life Sci 65 (22), 3606-3618 (2008)
   PUBMED   18695941
REFERENCE   3  (residues 1 to 129)
  AUTHORS   Whitman,C.P.
  TITLE     The 4-oxalocrotonate tautomerase family of enzymes: how nature
            makes new enzymes using a beta-alpha-beta structural motif
  JOURNAL   Arch Biochem Biophys 402 (1), 1-13 (2002)
   PUBMED   12051677
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: Conserved Domain (CDD)
            Evidence Accession :: Domain architecture ID 10216049
            Evidence Source    :: NCBI SPARCLE
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..129
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..129
                     /product="tautomerase family protein"
                     /GO_function="GO:0016853 - isomerase activity [Evidence
                     IEA]"
                     /calculated_mol_wt=14536
     Region          2..59
                     /region_name="4Oxalocrotonate_Tautomerase"
                     /note="4-Oxalocrotonate Tautomerase: Catalyzes the
                     isomerization of unsaturated ketones. The structure is a
                     homohexamer that is arranged as a trimer of dimers. The
                     hexamer contains six active sites, each formed by residues
                     from three monomers, two from one...; cl00235"
                     /db_xref="CDD:444774"
     Region          38..118
                     /region_name="Tautomerase_2"
                     /note="Tautomerase enzyme; pfam14552"
                     /db_xref="CDD:434035"
ORIGIN      
        1 mplltfdlie grteqevktl ldaahravlr afevperdry qivhenkahh mviedtglgl
       61 trtrdlvvvr vytsprseaq kqrffailqe elaehcglsg ddlmvsiisn qkgdwsfgrg
      121 vaqyltgdl