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SUMF1/EgtB/PvdO family nonheme iron enzyme [Klebsiella pneumoniae].


LOCUS       WP_004164123             117 aa            linear   BCT 02-MAR-2025
ACCESSION   WP_004164123
VERSION     WP_004164123.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella pneumoniae
  ORGANISM  Klebsiella pneumoniae
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group;
            Klebsiella; Klebsiella pneumoniae complex.
REFERENCE   1  (residues 1 to 117)
  AUTHORS   Seebeck,F.P.
  TITLE     In vitro reconstitution of Mycobacterial ergothioneine biosynthesis
  JOURNAL   J Am Chem Soc 132 (19), 6632-6633 (2010)
   PUBMED   20420449
REFERENCE   2  (residues 1 to 117)
  AUTHORS   Schlotawa,L., Steinfeld,R., von Figura,K., Dierks,T. and Gartner,J.
  TITLE     Molecular analysis of SUMF1 mutations: stability and residual
            activity of mutant formylglycine-generating enzyme determine
            disease severity in multiple sulfatase deficiency
  JOURNAL   Hum Mutat 29 (1), 205 (2008)
   PUBMED   18157819
REFERENCE   3  (residues 1 to 117)
  AUTHORS   Dierks,T., Dickmanns,A., Preusser-Kunze,A., Schmidt,B.,
            Mariappan,M., von Figura,K., Ficner,R. and Rudolph,M.G.
  TITLE     Molecular basis for multiple sulfatase deficiency and mechanism for
            formylglycine generation of the human formylglycine-generating
            enzyme
  JOURNAL   Cell 121 (4), 541-552 (2005)
   PUBMED   15907468
REFERENCE   4  (residues 1 to 117)
  AUTHORS   Cosma,M.P., Pepe,S., Parenti,G., Settembre,C., Annunziata,I.,
            Wade-Martins,R., Di Domenico,C., Di Natale,P., Mankad,A., Cox,B.,
            Uziel,G., Mancini,G.M., Zammarchi,E., Donati,M.A., Kleijer,W.J.,
            Filocamo,M., Carrozzo,R., Carella,M. and Ballabio,A.
  TITLE     Molecular and functional analysis of SUMF1 mutations in multiple
            sulfatase deficiency
  JOURNAL   Hum Mutat 23 (6), 576-581 (2004)
   PUBMED   15146462
REFERENCE   5  (residues 1 to 117)
  AUTHORS   Seshadri,R., Myers,G.S., Tettelin,H., Eisen,J.A., Heidelberg,J.F.,
            Dodson,R.J., Davidsen,T.M., DeBoy,R.T., Fouts,D.E., Haft,D.H.,
            Selengut,J., Ren,Q., Brinkac,L.M., Madupu,R., Kolonay,J.,
            Durkin,S.A., Daugherty,S.C., Shetty,J., Shvartsbeyn,A.,
            Gebregeorgis,E., Geer,K., Tsegaye,G., Malek,J., Ayodeji,B.,
            Shatsman,S., McLeod,M.P., Smajs,D., Howell,J.K., Pal,S., Amin,A.,
            Vashisth,P., McNeill,T.Z., Xiang,Q., Sodergren,E., Baca,E.,
            Weinstock,G.M., Norris,S.J., Fraser,C.M. and Paulsen,I.T.
  TITLE     Comparison of the genome of the oral pathogen Treponema denticola
            with other spirochete genomes
  JOURNAL   Proc Natl Acad Sci U S A 101 (15), 5646-5651 (2004)
   PUBMED   15064399
REFERENCE   6  (residues 1 to 117)
  AUTHORS   Landgrebe,J., Dierks,T., Schmidt,B. and von Figura,K.
  TITLE     The human SUMF1 gene, required for posttranslational sulfatase
            modification, defines a new gene family which is conserved from
            pro- to eukaryotes
  JOURNAL   Gene 316, 47-56 (2003)
   PUBMED   14563551
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF015722.6
            Evidence Source    :: EMBL-EBI
            Source Identifier  :: PF03781.22
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..117
                     /organism="Klebsiella pneumoniae"
                     /db_xref="taxon:573"
     Protein         1..117
                     /product="SUMF1/EgtB/PvdO family nonheme iron enzyme"
                     /calculated_mol_wt=12789
     Region          40..>97
                     /region_name="YfmG"
                     /note="Formylglycine-generating enzyme, required for
                     sulfatase activity, contains SUMF1/FGE domain
                     [Posttranslational modification, protein turnover,
                     chaperones]; COG1262"
                     /db_xref="CDD:440874"
ORIGIN      
        1 miklivvasv aaslllgcdq gnttgsekaa kalvdksvsn mvpvqggefl mgdfgplvge
       61 kllfsiqqdd ktlhkvilsd fsiskykvtn ddfnvylkvt dkkihlwiyw qnvillc