Unfortunately due to lack of commercial feasibility, the SkyBLAST service has been suspended from December 1st, 2025.
All subscriptions for paid accounts have been paused. For further information or enquiries, please email [email protected]
LOCUS WP_004152513 274 aa linear BCT 31-DEC-2024 ACCESSION WP_004152513 VERSION WP_004152513.1 KEYWORDS RefSeq. SOURCE Klebsiella ORGANISM Klebsiella Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group. REFERENCE 1 (residues 1 to 274) AUTHORS Kallberg,Y., Oppermann,U. and Persson,B. TITLE Classification of the short-chain dehydrogenase/reductase superfamily using hidden Markov models JOURNAL FEBS J 277 (10), 2375-2386 (2010) PUBMED 20423462 REFERENCE 2 (residues 1 to 274) AUTHORS Persson,B., Kallberg,Y., Bray,J.E., Bruford,E., Dellaporta,S.L., Favia,A.D., Duarte,R.G., Jornvall,H., Kavanagh,K.L., Kedishvili,N., Kisiela,M., Maser,E., Mindnich,R., Orchard,S., Penning,T.M., Thornton,J.M., Adamski,J. and Oppermann,U. TITLE The SDR (short-chain dehydrogenase/reductase and related enzymes) nomenclature initiative JOURNAL Chem Biol Interact 178 (1-3), 94-98 (2009) PUBMED 19027726 REFERENCE 3 (residues 1 to 274) AUTHORS Kavanagh,K.L., Jornvall,H., Persson,B. and Oppermann,U. TITLE Medium- and short-chain dehydrogenase/reductase gene and protein families : the SDR superfamily: functional and structural diversity within a family of metabolic and regulatory enzymes JOURNAL Cell Mol Life Sci 65 (24), 3895-3906 (2008) PUBMED 19011750 REFERENCE 4 (residues 1 to 274) AUTHORS Ladenstein,R., Winberg,J.O. and Benach,J. TITLE Medium- and short-chain dehydrogenase/reductase gene and protein families : Structure-function relationships in short-chain alcohol dehydrogenases JOURNAL Cell Mol Life Sci 65 (24), 3918-3935 (2008) PUBMED 19011748 REFERENCE 5 (residues 1 to 274) AUTHORS Oppermann,U., Filling,C., Hult,M., Shafqat,N., Wu,X., Lindh,M., Shafqat,J., Nordling,E., Kallberg,Y., Persson,B. and Jornvall,H. TITLE Short-chain dehydrogenases/reductases (SDR): the 2002 update JOURNAL Chem Biol Interact 143-144, 247-253 (2003) PUBMED 12604210 COMMENT REFSEQ: This record represents a single, non-redundant, protein sequence which may be annotated on many different RefSeq genomes from the same, or different, species. ##Evidence-For-Name-Assignment-START## Evidence Category :: Conserved Domain (CDD) Evidence Accession :: Domain architecture ID 10142954 Evidence Source :: NCBI SPARCLE ##Evidence-For-Name-Assignment-END## COMPLETENESS: full length. FEATURES Location/Qualifiers source 1..274 /organism="Klebsiella" /db_xref="taxon:570" Protein 1..274 /product="SDR family oxidoreductase" /EC_number="1.-.-.-" /GO_function="GO:0016491 - oxidoreductase activity [Evidence IEA]" /GO_function="GO:0051287 - NAD binding [Evidence IEA]" /calculated_mol_wt=29484 Region 4..259 /region_name="SDR_a4" /note="atypical (a) SDRs, subgroup 4; cd05266" /db_xref="CDD:187576" Site order(8,10..12,31..33,75..77,110..112,135,139,159..162) /site_type="other" /note="putative NAD(P) binding site [chemical binding]" /db_xref="CDD:187576" ORIGIN 1 mkkvaivglg wlgmplalsl targwqvtgs kttqdgveaa rmcgidsypl rlepqlvcdt 61 edldalmnvd alvitlparr tgagegfylq avqeivdtal ayhiprivft sstsvygnvn 121 gtvkensprl pqtasgqvlk eledwlhnlp gtsvdilrla glvgpsrhpg rffagksapd 181 gqhvvnlvhl qdvvaaiell lqapkgghiy nlcaprhpar glfypqmare lglpppvfsd 241 spdggqgkiv dgnricnelg feyqypdplv mpme