MULTISPECIES: 3D-(3,5/4)-trihydroxycyclohexane-1,2-dione

LOCUS       WP_004152191             646 aa            linear   BCT 01-JUL-2024
            acylhydrolase (decyclizing) [Klebsiella].
ACCESSION   WP_004152191
VERSION     WP_004152191.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 646)
  AUTHORS   Yoshida,K., Yamaguchi,M., Morinaga,T., Kinehara,M., Ikeuchi,M.,
            Ashida,H. and Fujita,Y.
  TITLE     myo-Inositol catabolism in Bacillus subtilis
  JOURNAL   J Biol Chem 283 (16), 10415-10424 (2008)
   PUBMED   18310071
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR04377.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..646
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..646
                     /gene="iolD"
     Protein         1..646
                     /product="3D-(3,5/4)-trihydroxycyclohexane-1,2-dione
                     acylhydrolase (decyclizing)"
                     /EC_number="3.7.1.22"
                     /GO_function="GO:0016823 - hydrolase activity, acting on
                     acid carbon-carbon bonds, in ketonic substances [Evidence
                     IEA]"
                     /GO_function="GO:0030976 - thiamine pyrophosphate binding
                     [Evidence IEA]"
                     /GO_process="GO:0019310 - inositol catabolic process
                     [Evidence IEA]"
                     /calculated_mol_wt=70625
     Region          1..646
                     /region_name="IolD"
                     /note="TPP-dependent trihydroxycyclohexane-1,2-dione
                     (THcHDO) dehydratase, myo-inositol metabolism
                     [Carbohydrate transport and metabolism]; COG3962"
                     /db_xref="CDD:443162"
ORIGIN      
        1 mgklrlttaq alvkfldnqy levdgvelkf vkgifaifgh gnvlglgqal eqdsgdmrvy
       61 qgrneqgmah aatgfarqal rrqiiactss igpgaanmit aagtasanri pllllpgdvf
      121 atrqpdpvlq qieqsydlsi stndafravs kywdritrpe qlmsacinam rvltdpaetg
      181 avtlclpqdv qgeawdypes ffarrvhrld rrpasaaqla davaaikasr kplivcgggv
      241 kysgageals rfaerygvpf aetqagkgtv vsshplnvgg vgetgclaan llakeadlvi
      301 gvgtrfsdft taskwifqhp evrflninvs nfdawkldgi amladaream taldaalads
      361 gwqagwgaqi esvqsrqlke tqrvyqavwq eksfvpeidd hldresvyre frqitdstlt
      421 qssvlgvlne tlpaeaviva aagslpgdlq rvwrnraent yhveygyscm gyevnaalgv
      481 klaqpqsevy slvgdgsfmm lhselvtslq erakinvvlf dnmangcinn lqmehgmdsf
      541 gtefryrqpe tgqlqgglvp vdfatiaagy gcktwrvttl delrhaldaa rretvstlid
      601 ikvlpktmvh kygswwnvgv aqtalserir kvaqminekr aqardy