MULTISPECIES: sulfatase-like hydrolase/transferase [Klebsiella].

LOCUS       WP_004152009             622 aa            linear   BCT 02-MAR-2025
ACCESSION   WP_004152009
VERSION     WP_004152009.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 622)
  AUTHORS   Lukatela,G., Krauss,N., Theis,K., Selmer,T., Gieselmann,V., von
            Figura,K. and Saenger,W.
  TITLE     Crystal structure of human arylsulfatase A: the aldehyde function
            and the metal ion at the active site suggest a novel mechanism for
            sulfate ester hydrolysis
  JOURNAL   Biochemistry 37 (11), 3654-3664 (1998)
   PUBMED   9521684
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF013080.6
            Evidence Source    :: EMBL-EBI
            Source Identifier  :: PF00884.28
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..622
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     Protein         1..622
                     /product="sulfatase-like hydrolase/transferase"
                     /GO_function="GO:0008484 - sulfuric ester hydrolase
                     activity [Evidence IEA]"
                     /calculated_mol_wt=71136
     Region          60..474
                     /region_name="sulfatase_like"
                     /note="uncharacterized sulfatase subfamily; cd16035"
                     /db_xref="CDD:293759"
     Site            order(68..69,102..103,157,159,250,376..377)
                     /site_type="active"
                     /note="putative active site [active]"
                     /db_xref="CDD:293759"
     Site            order(68..69,103,157,159,250,377)
                     /site_type="other"
                     /note="putative substrate binding site [chemical binding]"
                     /db_xref="CDD:293759"
     Region          <553..588
                     /region_name="DUF4976"
                     /note="Domain of unknown function (DUF4976); cl20644"
                     /db_xref="CDD:419068"
ORIGIN      
        1 mkepnkidgn rrhllkglgi aavvsllpet gnaaqnnaap kaawdipftg eipdtlpegy
       61 nillitcdqe ryferypfpv pgrerlmktg itftnhqnta nvctpsrsvm ytglhmphtr
      121 mfdnlgfpwm nydldpelrt vghmmrelgy ytaykgkwhl treidqpvag ksveemdlge
      181 iptprlheim ekygfsdyhg igdvigkskg gyffdsvttg qtiswlrntg rplndenkpw
      241 faavnlvnph dvmfidtdeh geqvqwkgpm dkenhtllpt qpphnqiyqq swpdyplpan
      301 rhqpldepgr paahkeyqna ravmegqfpd edrrwrklld yyfncirdnd qhleailnel
      361 dnlqltqnti ivftadhgel ggshqmhgkg ssvykeqihv pmiirhpayp gnircnsltn
      421 hldlvptlig ltgrdrslre kvlegrkgrd mspllahpeq aglnalrpgs lycygmilym
      481 daqytakfrk lageklphdq fkkaiaslhp dfshrsgirm indghykfar yfslkqhhip
      541 atlaellenn dvelfdlvnd peenhnlare pekyrdllmt mndklnqlta aeigeddgsy
      601 mppfegsqwd msaaqmhqym rd