MULTISPECIES: glutamine-hydrolyzing GMP synthase [Klebsiella].

LOCUS       WP_004151979             525 aa            linear   BCT 20-NOV-2023
ACCESSION   WP_004151979
VERSION     WP_004151979.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 525)
  AUTHORS   Tesmer,J.J., Klem,T.J., Deras,M.L., Davisson,V.J. and Smith,J.L.
  TITLE     The crystal structure of GMP synthetase reveals a novel catalytic
            triad and is a structural paradigm for two enzyme families
  JOURNAL   Nat. Struct. Biol. 3 (1), 74-86 (1996)
   PUBMED   8548458
REFERENCE   2  (residues 1 to 525)
  AUTHORS   Tesmer,J.J., Stemmler,T.L., Penner-Hahn,J.E., Davisson,V.J. and
            Smith,J.L.
  TITLE     Preliminary X-ray analysis of Escherichia coli GMP synthetase:
            determination of anomalous scattering factors for a cysteinyl
            mercury derivative
  JOURNAL   Proteins 18 (4), 394-403 (1994)
   PUBMED   8208731
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF000848.0
            Evidence Source    :: NCBI Protein Cluster (PRK)
            Source Identifier  :: PRK00074
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..525
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..525
                     /gene="guaA"
     Protein         1..525
                     /product="glutamine-hydrolyzing GMP synthase"
                     /EC_number="6.3.5.2"
                     /GO_function="GO:0003922 - GMP synthase
                     (glutamine-hydrolyzing) activity [Evidence IEA]"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016462 - pyrophosphatase activity
                     [Evidence IEA]"
                     /GO_process="GO:0006177 - GMP biosynthetic process
                     [Evidence IEA]"
                     /calculated_mol_wt=58661
     Region          5..525
                     /region_name="guaA"
                     /note="GMP synthase; Reviewed; PRK00074"
                     /db_xref="CDD:234614"
ORIGIN      
        1 mtenihkhri lildfgsqyt qlvarrvrel gvycelwawd vteaqirefn psgiilsggp
       61 estteenspr apqyvfeagv pvfgvcygmq tmamqlgghv egsnerefgy aqvevvndsa
      121 lvrgiedslt adgkplldvw mshgdkvtai padfvtvast dncpfaiman eekrfygvqf
      181 hpevthtrqg mrmlerfvrd icqcealwtp akiiddaver irqqvgddkv ilglsggvds
      241 svtamllhra igknltcvfv dngllrlnea qqvmemfgdh fglnivhveg eqrfldalag
      301 esdpeakrki igrvfvevfd eealklddvk wlaqgtiypd viesaasatg kahvikshhn
      361 vgglpkemkm glveplrelf kdevrkigle lglpydmlyr hpfpgpglgv rvlgevkkey
      421 cdllrradai fieelhkadl ynkvsqaftv flpvrsvgvm gdgrkydwvv slravetidf
      481 mtahwahlpy dflgrvsnri inevngisrv vydisgkppa tiewe