MULTISPECIES: 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase

LOCUS       WP_004151837             288 aa            linear   BCT 03-OCT-2023
            [Klebsiella].
ACCESSION   WP_004151837
VERSION     WP_004151837.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 288)
  AUTHORS   Li,C., Li,J.J., Montgomery,M.G., Wood,S.P. and Bugg,T.D.
  TITLE     Catalytic role for arginine 188 in the C-C hydrolase catalytic
            mechanism for Escherichia coli MhpC and Burkholderia xenovorans
            LB400 BphD
  JOURNAL   Biochemistry 45 (41), 12470-12479 (2006)
   PUBMED   17029402
REFERENCE   2  (residues 1 to 288)
  AUTHORS   Dunn,G., Montgomery,M.G., Mohammed,F., Coker,A., Cooper,J.B.,
            Robertson,T., Garcia,J.L., Bugg,T.D. and Wood,S.P.
  TITLE     The structure of the C-C bond hydrolase MhpC provides insights into
            its catalytic mechanism
  JOURNAL   J Mol Biol 346 (1), 253-265 (2005)
   PUBMED   15663942
REFERENCE   3  (residues 1 to 288)
  AUTHORS   Li,C., Montgomery,M.G., Mohammed,F., Li,J.J., Wood,S.P. and
            Bugg,T.D.
  TITLE     Catalytic mechanism of C-C hydrolase MhpC from Escherichia coli:
            kinetic analysis of His263 and Ser110 site-directed mutants
  JOURNAL   J Mol Biol 346 (1), 241-251 (2005)
   PUBMED   15663941
REFERENCE   4  (residues 1 to 288)
  AUTHORS   Ferrandez,A., Garcia,J.L. and Diaz,E.
  TITLE     Genetic characterization and expression in heterologous hosts of
            the 3-(3-hydroxyphenyl)propionate catabolic pathway of Escherichia
            coli K-12
  JOURNAL   J Bacteriol 179 (8), 2573-2581 (1997)
   PUBMED   9098055
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: BlastRule
            Evidence Accession :: NBR011011
            Evidence Source    :: NCBI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..288
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..288
                     /gene="mhpC"
     Protein         1..288
                     /product="2-hydroxy-6-oxonona-2,4-dienedioate hydrolase"
                     /EC_number="3.7.1.14"
                     /calculated_mol_wt=31578
     Region          7..286
                     /region_name="biphenyl_bphD"
                     /note="2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate
                     hydrolase; TIGR03343"
                     /db_xref="CDD:132386"
ORIGIN      
        1 msyqpqteaa tsrflnvdeg grtlrihind cgdgketvvm lhgsgpgatg wanfsrnidp
       61 lveagyrvll ldcpgwgksd aivnsgsrsd lnarilksvv dqlgidkvhl lgnsmgghsa
      121 vaftlswper vaklvlmggg tggmslftpm ptegikllna lyreptienl kkmmsifvfd
      181 trdltealfe arlnnmlsrr dhldnfvksl eanpkqfpdf gprlgeisap tlivwgrndr
      241 fvpmdaglrl lagiagselh iyrdcghwaq wehadsfnql vlnflara