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MULTISPECIES: phosphonate metabolism protein PhnP [Klebsiella].


LOCUS       WP_004151728             252 aa            linear   BCT 24-MAR-2022
ACCESSION   WP_004151728
VERSION     WP_004151728.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 252)
  AUTHORS   He,S.M., Wathier,M., Podzelinska,K., Wong,M., McSorley,F.R.,
            Asfaw,A., Hove-Jensen,B., Jia,Z. and Zechel,D.L.
  TITLE     Structure and mechanism of PhnP, a phosphodiesterase of the
            carbon-phosphorus lyase pathway
  JOURNAL   Biochemistry 50 (40), 8603-8615 (2011)
   PUBMED   21830807
REFERENCE   2  (residues 1 to 252)
  AUTHORS   Hove-Jensen,B., McSorley,F.R. and Zechel,D.L.
  TITLE     Physiological role of phnP-specified phosphoribosyl cyclic
            phosphodiesterase in catabolism of organophosphonic acids by the
            carbon-phosphorus lyase pathway
  JOURNAL   J Am Chem Soc 133 (10), 3617-3624 (2011)
   PUBMED   21341651
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: TIGR03307.1
            Evidence Source    :: JCVI
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..252
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..252
                     /gene="phnP"
     Protein         1..252
                     /product="phosphonate metabolism protein PhnP"
                     /EC_number="3.1.4.55"
                     /GO_function="GO:0008081 - phosphoric diester hydrolase
                     activity [Evidence IEA]"
                     /GO_process="GO:0019700 - organic phosphonate catabolic
                     process [Evidence IEA]"
                     /calculated_mol_wt=27786
     Region          13..249
                     /region_name="metallo-hydrolase-like_MBL-fold"
                     /note="mainly hydrolytic enzymes and related proteins
                     which carry out various biological functions; MBL-fold
                     metallohydrolase domain; cl23716"
                     /db_xref="CDD:451500"
     Site            order(76,78,80..81,143,164)
                     /site_type="active"
                     /db_xref="CDD:293822"
ORIGIN      
        1 msltlrltgt ggaqlvpvfg cdcaacrrar reeshrrrpc sgvvtfnsav tlldagrpdl
       61 mehhpagsfq qvllthyhld hvqglfplrw gvgasipvyg ppddagcddl lkhpglldfs
      121 htvtpfvmfn lqglrvtplp lnhskltfgy llesahsrla wlsdtaglpd ktlkfllnnr
      181 pqamiidcsh epraqtprnh ndlntvrsln qvigcprvil thishqfdvw mmdnplptgf
      241 eagydgmeia ld