MULTISPECIES: D-threonate kinase [Klebsiella].

LOCUS       WP_004151622             411 aa            linear   BCT 25-NOV-2024
ACCESSION   WP_004151622
VERSION     WP_004151622.1
KEYWORDS    RefSeq.
SOURCE      Klebsiella
  ORGANISM  Klebsiella
            Bacteria; Pseudomonadati; Pseudomonadota; Gammaproteobacteria;
            Enterobacterales; Enterobacteriaceae; Klebsiella/Raoultella group.
REFERENCE   1  (residues 1 to 411)
  AUTHORS   Thiaville,J.J., Flood,J., Yurgel,S., Prunetti,L.,
            Elbadawi-Sidhu,M., Hutinet,G., Forouhar,F., Zhang,X., Ganesan,V.,
            Reddy,P., Fiehn,O., Gerlt,J.A., Hunt,J.F., Copley,S.D. and de
            Crecy-Lagard,V.
  TITLE     Members of a Novel Kinase Family (DUF1537) Can Recycle Toxic
            Intermediates into an Essential Metabolite
  JOURNAL   ACS Chem Biol 11 (8), 2304-2311 (2016)
   PUBMED   27294475
REFERENCE   2  (residues 1 to 411)
  AUTHORS   Zhang,X., Carter,M.S., Vetting,M.W., San Francisco,B., Zhao,S.,
            Al-Obaidi,N.F., Solbiati,J.O., Thiaville,J.J., de Crecy-Lagard,V.,
            Jacobson,M.P., Almo,S.C. and Gerlt,J.A.
  TITLE     Assignment of function to a domain of unknown function: DUF1537 is
            a new kinase family in catabolic pathways for acid sugars
  JOURNAL   Proc Natl Acad Sci U S A 113 (29), E4161-E4169 (2016)
   PUBMED   27402745
COMMENT     REFSEQ: This record represents a single, non-redundant, protein
            sequence which may be annotated on many different RefSeq genomes
            from the same, or different, species.
            
            ##Evidence-For-Name-Assignment-START##
            Evidence Category  :: HMM
            Evidence Accession :: NF047819.1
            Evidence Source    :: NCBIFAM
            ##Evidence-For-Name-Assignment-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..411
                     /organism="Klebsiella"
                     /db_xref="taxon:570"
     gene            1..411
                     /gene="dtnK"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016301 - kinase activity [Evidence IEA]"
     Protein         1..411
                     /product="D-threonate kinase"
                     /EC_number="2.7.1.219"
                     /GO_function="GO:0005524 - ATP binding [Evidence IEA]"
                     /GO_function="GO:0016301 - kinase activity [Evidence IEA]"
                     /calculated_mol_wt=43360
     Region          7..408
                     /region_name="OtnK"
                     /note="D-threonate/D-erythronate kinase OtnK and related
                     C4-acid sugar kinases, YgbK/DUF1537 family [Carbohydrate
                     transport and metabolism]; COG3395"
                     /db_xref="CDD:442622"
ORIGIN      
        1 mndrnnrvlv laddftgand agvslaeagm svevaftagq pstaraliln sdsramtaaa
       61 aadkvaallr gaatfvphwq vkkidstlrg npggeleamm aaqgcrmavv apaypaagrh
      121 trdgrcyvhg vpldqtefas dpktpvsrae iseiiamqsr lpcltlnagq lpaalatage
      181 ekrvlivdaw edshldqvid avapharetl lvgsaglcea larrlrrseq gplmavvgsm
      241 semaqrqvaa lqvhsrvrvi eidveqtfsg spkeeasria galregqhcv vttrpnhaar
      301 hgiearcrer glsraaygeh icawladvta qavaqsspga lylsggdvai avahalgatg
      361 fqirgrvaec vpyghflggr wsrpvmtkag gfgtdttllh vvnfieekls v